5G is being implemented in the Internet of things (IoT) era. This book chapter focuses on 5G technology and the integration of other digital technologies, such as artificial intelligence (AI) and machine learning, IoT, big data analytics, cloud computing, robotics, and other digital platforms into new healthcare applications. Now, the healthcare industry is implementing 5G-enabled technology to improve health services, medical research, quality of life, and medical professionals’ and patients’ experiences everywhere, at any time. Technology can facilitate faster medical research progress and better clinical and social services management. Furthermore, AI approaches with 5G connectivity may be able to combat the epidemic challenges with minimal resources. This book chapter underlines how 5G technology is growing to address epidemic concerns. The study highlights many technical issues and future developments for creating 5G-powered healthcare solutions. This chapter also addresses the key challenges AI and 5G technology face in emerging healthcare solutions. In addition, this book chapter highlights perspective, policy recommendations, and future research directions of AI and 5G-enabled technologies in confronting future pandemics. More research will be incorporated into future projects, including studies on developing a digital society based on 5G technology in healthcare emergencies.