The expression and correlation of Hsp 70 and Hsp 27 in serous middle ear effusion fluids of pediatric patients-a preliminary study

Min, Hyun Jin; Choe, Ji Won; Chang, Moon Young; Kim, Kyung Soo; Lee, Sei Young; Mun, Seog‐Kyun

doi:10.1016/j.ijporl.2017.08.009

Cited by 4 publications

(3 citation statements)

References 27 publications

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“…Оксидативный стресс сопровождается усиленным синтезом sHsp -они активируют или стабилизируют глюкозо-6-фосфат дегидрогеназу, фермент, продуктом которого является НАДН. Повышение уровня НАДНДГ увеличивает активность глутатион-редуктазы, что обеспечивает поддержание нормального уровня вос-становленного глутатиона, фактора антиоксидантной защиты [11,22,28].…”

Section: таблица белки теплового шока в эукариотических клеткахunclassified

“…В клетках млекопитающих транскрипция генов HSP70 возникает очень быстро после стресса, и их матрицы транслируются с более высокой эффективностью. Уровни экспрессии генов HSP70 зависят от типа клеток и возрастают в следующей последовательности: печень -> кишечник -> селезенка -> почка -> легкое -> сердце -> мозг [7,22].…”

Section: таблица белки теплового шока в эукариотических клеткахunclassified

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Heat Shock Proteins. Properties. Role in Adaptation. Methodological Approaches to Definition

Максимович

Бонь

2020

BIOMEDICINE

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The aim of this review article is to generalize and systematize literature data on the properties of heat shock proteins, as well as their role in adaptation processes and experimental methods of their investigation. The synthesis of heat shock proteins is a universal response to stress, which plays an important role in protecting cells from negative external impacts. Heat shock proteins participate in fundamental cellular processes. Altered expression of heat shock proteins can serve as an important diagnostic marker of cellular responses to damage.

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Section: таблица белки теплового шока в эукариотических клеткахunclassified

Heat Shock Proteins. Properties. Role in Adaptation. Methodological Approaches to Definition

Максимович

Бонь

2020

BIOMEDICINE

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“…The PET-CT imaging is a method combining molecular metabolism with anatomical structure images. It has obvious advantages in early identification and diagnosis of most diseases [ 9 ]. The detection method is easy to operate and noninvasive and lets patients suffer little pain.…”

Section: Introductionmentioning

confidence: 99%

Clone Selection Artificial Intelligence Algorithm-Based Positron Emission Tomography-Computed Tomography Image Information Data Analysis for the Qualitative Diagnosis of Serous Cavity Effusion in Patients with Malignant Tumors

Wei

Zhang

et al. 2021

Journal of Healthcare Engineering

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This study aimed to investigate the application of positron emission tomography- (PET-) computed tomography (CT) image information data combined with serous cavity effusion based on clone selection artificial intelligence algorithm in the diagnosis of patients with malignant tumors. A total of 97 patients with PET-CT scanning and empirically confirmed as serous cavity effusion were retrospectively analyzed in this study. The clone selection artificial intelligence algorithm was applied to register the PET-CT images, and the patients were rolled into a benign effusion group and a malignant effusion group according to the benign and malignant conditions of the serous cavity effusion. Besides, the causes of patients from the two groups were analyzed, and there was a comparison of their physiological conditions. Subsequently, CT values of different KeV, lipid/water, water/iodine, and water/calcium concentrations were measured, and the differences of the above quantitative parameters between benign and malignant serous cavity effusion were compared, as well as the registration results of the clone algorithm. The results showed that the registration time and misalignment times of clonal selection algorithm (13.88, 0) were lower than those of genetic algorithm (18.72, 8). There were marked differences in CT values of 40–60 keV and 130–140 keV between the two groups. The concentrations of lipid/water, water/iodine, and water/calcium in basal substances of the malignant effusion group were obviously higher than the concentrations of the benign effusion group ( P < 0.05 ). Benign and malignant effusions presented different manifestations in PET-CT, which was conducive to the further diagnosis of malignant tumors. Based on clone selection artificial intelligence algorithm, PET-CT could provide a new multiparameter method for the identification of benign and malignant serous cavity effusions and benign and malignant tumors.

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Introduction to Rare Genetic Disorders

Parthasarathy,

Raju,

Kulanthaivel

et al. 2024

Rare Genetic Disorders

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The expression and correlation of Hsp 70 and Hsp 27 in serous middle ear effusion fluids of pediatric patients-a preliminary study

Cited by 4 publications

References 27 publications

Heat Shock Proteins. Properties. Role in Adaptation. Methodological Approaches to Definition

Heat Shock Proteins. Properties. Role in Adaptation. Methodological Approaches to Definition

Clone Selection Artificial Intelligence Algorithm-Based Positron Emission Tomography-Computed Tomography Image Information Data Analysis for the Qualitative Diagnosis of Serous Cavity Effusion in Patients with Malignant Tumors

Introduction to Rare Genetic Disorders

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