The extraction, antioxidant and against β-amyloid induced toxicity of polyphenols from Alsophila spinulosa leaves

Yan, Ningning; Zhang, Huifang; Zhang, Zhonghao; Zhou, Lijun; Chen, Tao; Feng, Shiling; Ding, Chunbang; Yuan, Ming

doi:10.1016/j.arabjc.2022.103707

Cited by 9 publications

(4 citation statements)

References 35 publications

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“…Although experimental design is a widely used tool in the optimization of extraction processes whenever several factors may affect the response to be optimized, it has been used less profusely in the extraction of polyphenols for studies in Alzheimer’s disease, and in the studies in which it has been used, the methodology of response surface analysis is used to evaluate parameters related to anti-AChE capacity [ 67 ] or in survival studies in in vivo trials [ 138 ].…”

Section: Polyphenols and Their Obtentionmentioning

confidence: 99%

“…The optimization of the extraction of bioactive compounds in Tamarillo [ 67 ] was carried out using a central composite design and using the response surface methodology, two factors (solvent composition and temperature) and three levels have been considered, and among the responses to be optimized was the anti-AChE capacity, a response that was adjusted to a quadratic model that allows to observe that temperatures of 180 °C allow extracts to be obtained rich in flavonoids, polyphenols, and carotenoids with promising antioxidant, anti-inflammatory, and anti-AChE activity. A Box–Behnken design and response surface analysis used Yan et al [ 138 ] to optimize the extraction of leaves of Alsophila spinulosa and extracts were used to increase the survival of C. elegans subjected to high temperature.…”

Section: Polyphenols and Their Obtentionmentioning

confidence: 99%

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A Comprehensive Analytical Review of Polyphenols: Evaluating Neuroprotection in Alzheimer’s Disease

Vicente-Zurdo,

Gómez-Mejía,

Rosales-Conrado

et al. 2024

IJMS

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Alzheimer’s Disease (AD), a prevalent neurodegenerative disorder, is the primary cause of dementia. Despite significant advancements in neuroscience, a definitive cure or treatment for this debilitating disease remains elusive. A notable characteristic of AD is oxidative stress, which has been identified as a potential therapeutic target. Polyphenols, secondary metabolites of plant origin, have attracted attention due to their potent antioxidant properties. Epidemiological studies suggest a correlation between the consumption of polyphenol-rich foods and the prevention of chronic diseases, including neurodegenerative disorders, which underscores the potential of polyphenols as a therapeutic strategy in AD management. Hence, this comprehensive review focuses on the diverse roles of polyphenols in AD, with a particular emphasis on neuroprotective potential. Scopus, ScienceDirect, and Google Scholar were used as leading databases for study selection, from 2018 to late March 2024. Analytical chemistry serves as a crucial tool for characterizing polyphenols, with a nuanced exploration of their extraction methods from various sources, often employing chemometric techniques for a holistic interpretation of the advances in this field. Moreover, this review examines current in vitro and in vivo research, aiming to enhance the understanding of polyphenols’ role in AD, and providing valuable insights for forthcoming approaches in this context.

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Section: Polyphenols and Their Obtentionmentioning

confidence: 99%

Section: Polyphenols and Their Obtentionmentioning

confidence: 99%

A Comprehensive Analytical Review of Polyphenols: Evaluating Neuroprotection in Alzheimer’s Disease

Vicente-Zurdo,

Gómez-Mejía,

Rosales-Conrado

et al. 2024

IJMS

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“…Alsophila spinulosa is a large tree fern whose population structure can reflect its growth pattern. The spatial distribution and spatial linkage characteristics can reflect the spread range of spores and the characteristics of growth restriction [10]. Therefore, by studying the population structure and spatial characteristics of A. spinulos, the relationship between A. spinulos and the environment can be reflected, which has high practical significance.…”

Section: Introductionmentioning

confidence: 99%

Population Structure, Distribution, and Spatial Characteristics of Alsophila spinulosa in Chishui, China

Yuan,

Yang,

et al. 2023

Diversity

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Endangered plants are essential components of most forest ecosystems and reflect the ecological integrity of forests. The study of the population structure and spatial pattern of Alsophila spinulosa is of great significance for its conservation. In the subtropical Chishui Tree fern valley in China, we studied the best structure of A. spinulosa to reflect the environmental change, the range of the most intense spatial aggregation change, and the spatial relationship with the community structure, and explored the survival characteristics of A. spinulosa. Our results showed that the variation in tree height structure was the most obvious response to the change in community type. The spatial aggregation degree of A. spinulosa had the most obvious change in the range of 1–5 m. There was an obvious spatial correlation between the dominant plants, the vertical structure of the community, and the distribution of A. spinulosa. These findings provided a reference for exploring the population structure, distribution pattern, and the influence of community types on A. spinulosa populations.

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“…As a C-glycosylated avone, vitexin was isolated from various plants, such as hawthorn, mung bean, pearl millet, Passiora, pigeon pea, bamboo, wheat leaves, mimosa, chaste tree, etc. [1][2][3][4][5] It was reported to have anti-tumor, [6][7][8] anti-oxidant, 9 anti-viral, 10 and hepatoprotective activities. 11,12 Thus, vitexin is a potential phytochemical constituent for pharmaceutical usage.…”

Section: Introductionmentioning

confidence: 99%

Enzymatic synthesis of vitexin glycosides and their activity

Fan

Lou

et al. 2022

RSC Adv.

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The extraction, antioxidant and against β-amyloid induced toxicity of polyphenols from Alsophila spinulosa leaves

Cited by 9 publications

References 35 publications

A Comprehensive Analytical Review of Polyphenols: Evaluating Neuroprotection in Alzheimer’s Disease

A Comprehensive Analytical Review of Polyphenols: Evaluating Neuroprotection in Alzheimer’s Disease

Population Structure, Distribution, and Spatial Characteristics of Alsophila spinulosa in Chishui, China

Enzymatic synthesis of vitexin glycosides and their activity

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