The first <scp>BGICC</scp> consensus and recommendations for breast cancer awareness, early detection and risk reduction in low‐ and middle‐income countries and the <scp>MENA</scp> region

Elghazaly, Hesham; Aref, Adel T.; Anderson, Benjamin O.; Arun, Banu K.; Yip, Cheng Har; Abdel-Aziz, H; Ghosn, Marwan; Al‐Foheidi, Meteb; Cardenosa, G; Leung, Jessica W.T.; Gado, N.; Balch, Charles M.; Sabry, Mohamed; El-Arab, Lobna Ezz; Giuliano, Armando E.; El-Zawahry, Heba M.; Karim, Khaled Abdel; Nasr, Aml S.; Maki, Hussein; Chung, Hannah; Saadeddin, Ahmed; Abdelwahab, Manal M.; Tahan, Fatina M. Al; Chalabi, Nivine; Фролова, М. А.; Kamal, Rasha; Shehata, Mohamed; Eldin, Nermean Bahie; Elghazawy, Hagar

doi:10.1002/ijc.33506

Cited by 10 publications

(7 citation statements)

References 33 publications

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“…Takođe, ni kampanja, ni program nisu obezbedili edukaciju o ograničenom skupu faktora rizika i akcija koje se mogu preduzeti radi smanjivanja rizika od raka dojke za mnoge žene: izbegavanje nepotrebnog medicinskog zračenja tokom života, izbegavanje upotrebe nekih oblika hormonske terapije u postmenopauzi, izbegavanje pušenja, ograničavanje konzumacije alkoholnih pića, povećanje fizičke aktivnosti i minimiziranje povećanja telesne mase. Program podizanja svesti o raku dojke trebalo bi da bude usmeren na uključivanje strategija za smanjenje rizika, na javnost kroz kampanje sredstava javnog informisanja, na izabrane lekarespecijaliste opšte medicine, specijaliste ginekologije i akušerstva, kao i na mediicnske sestre [14]. Promocija bi trebalo da bude usmerena na sve starosne grupe odraslih , što će omogućiti unakrsnu izloženost društvenih i porodičnih mreža [14], kao i na učenike srednjih škola kroz uključivanje strategija za prevenciju raka dojke u redovni školski program [15].…”

Section: Uvodunclassified

“…Program podizanja svesti o raku dojke trebalo bi da bude usmeren na uključivanje strategija za smanjenje rizika, na javnost kroz kampanje sredstava javnog informisanja, na izabrane lekarespecijaliste opšte medicine, specijaliste ginekologije i akušerstva, kao i na mediicnske sestre [14]. Promocija bi trebalo da bude usmerena na sve starosne grupe odraslih , što će omogućiti unakrsnu izloženost društvenih i porodičnih mreža [14], kao i na učenike srednjih škola kroz uključivanje strategija za prevenciju raka dojke u redovni školski program [15]. Ključan momenat za unapređenje svesti je uključivanje žena u proces planiranja aktivnosti kako bi se postigao kulturološki i lingvistički specifičan pristup [6].…”

Section: Uvodunclassified

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Promocija zdravlja i komponente socijalnog marketinga u funkciji ranog otkrivanja raka dojke

Kilibarda¹,

Sinanović²,

Bubanj³

et al. 2021

Timočki medicinski glasnik

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Uvod. Socijalni marketing je strategija i sredstvo za dostizanje opšte društvene dobrobiti. Primena socijalnog marketinga u oblasti zdravlja ima za cilj očuvanje i unapređenje zdravlja i rano otkrivanje bolesti i veoma je zahtevna, a ishodi se mere konkretnim podacima o zdravlju stanovništva. Marketing miks u socijalnom marketingu se koristi u kampanjama za unapređenje zdravlja, naročito žena, a kroz socijalnu mobilizaciju za rano otkrivanje raka dojke. Ciljevi ovog rada su analiza sadržaja dve kampanje za prevenciju raka dojke u Srbiji i pregled ključnih iskustava iz njih. Metod. Rad se bazira na uporednoj analizi studija slučaja u Srbiji. Sagledavaju se prednosti i nedostaci dve kampanje za rano otkrivanje raka dojke koje su sproveli kompanija AVON i Ministarstvo zdravlja Republike Srbije u periodu od 2014. do 2020. godine, kao i pravci daljih istraživanja u oblasti socijalnog marketinga usmerenog ka primarnoj prevenciji i ranom otkrivanju bolesti. Zaključci: Prednosti pomenutih kampanja su: stratifikacija ciljnih grupa prema karakteristikama i specifičnostima i određivanje specifičnih strategija socijalnog marketinga za svaki stratum (na primer, za urbanu i ruralnu sredinu), kao i targetiranje ne samo usko specifične ciljne grupe, odnosno žena, već i grupe podrške (porodica, rodbina, prijatelji). Nedostaci kampanja su: slaba vidljivost aktivnosti, nemogućnost održavanja kontinuiteta aktivnosti socijalnog marketinga, nedovoljna posvećenost inoviranju sadržaja kampanja novodolazećim generacijama.

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Section: Uvodunclassified

Promocija zdravlja i komponente socijalnog marketinga u funkciji ranog otkrivanja raka dojke

Kilibarda¹,

Sinanović²,

Bubanj³

et al. 2021

Timočki medicinski glasnik

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show abstract

“…Although the survival rate of BC in the eastern world is decreasing, those in western countries are still increasing 1 , 3 . This type of cancer is the second most dangerous cancer-associated mortality after skin cancer, particularly in the US and middle east nations 4 – 6 . Genomic and epigenetic aberrations are found to be the main cause of the development of breast carcinogenesis.…”

Section: Introductionmentioning

confidence: 99%

The profiles of miR-4510 expression level in breast cancer

Majed

Mustafa²

2023

Sci Rep

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MicroRNA that is abnormally produced in breast cells can disrupt biological processes, which can lead to cancer. This study aims to screen differentially expressed genes (DEGs) and ncRNAs (DEncRNAs) in the formalin-fixed paraffin-embedded (FFPE) tissues of breast cancer (BC) as compared with the normal adjacent tissues (NAT), and identify miR-4510 as a novel biomarker of BC. This study looked at differentially expressed genes (DEGs) using MACE-Seq and differentially expressed ncRNAs (DEncRNAs) using the small RNA-Seq. Real-time qPCR was used to determine the level of expression of miR-4510. In this study, MACE-Seq results showed that 26,795 genes, with a p-value < 0.05, were differentially expressed in BC paraffin tissues as compared with NAT. Small RNA-Seq results revealed that 1326 ncRNAs, with a p-value < 0.05, were differentially expressed. We confirmed that miR-4510 was significantly down-expressed (p-value = 0.001) by qRT-PCR in the paraffin tissue of 120 BC patients. Based on eleven computational prediction programs, TP53, TP53INP1, MMP11, and COL1A1 for the miR-4510 were identified as miR-4510 targets. The MACE-seq result showed that the gene of TP53 (p-value = 0.001) and TP53INP1 (p-value = 0.02) was significantly down-regulated, but the gene of MMP11 (p-value = 0.004) and COL1A1 (p-value = 0.0001) was significantly over-expressed in 20 paired specimens of the BC and NAT. We discovered that a single SNP inside the miR-4510 binding site occurred only in BC, in which Guanine (G) changed into Adenine (A). Two SNPs outside the miR-4510 binding site occurred, and Guanine (G) in both BC and NAT was changed into Thymine (T), as compared to the reference sequence (RefSeq). Overall, our results suggested that miR-4510 functions as a tumor suppressor in the BC. Mir-4510 may act as a tumor suppressor, however additional experimental data is needed to corroborate these assumptions and can be exploited as a biomarker for BC.

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“…2 In many lower middle-income countries, mammography is poorly accessible and/or unaffordable that the population is forced to rely on breast self-examination and clinical breast examination as the basic early detecting methods for breast cancer. 3 Mammography is the only screening procedure proven to decrease deaths due to breast cancer. 4 In Asia, highest rate of breast cancer is of Pakistan, 5 this is likely to increase further in coming years.…”

Section: Introductionmentioning

confidence: 99%

Awareness Regarding Breast Cancer, Perceptions and Compliance towards Mammography among Women Visiting Tertiary Care Hospitals in Rawalpindi

Hisam

Mashhadi²,

Fatima³

et al. 2023

PAFMJ

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Objective: To find out awareness about breast cancer, perceptions and compliance towards mammography in women reporting to tertiary care hospitals in Rawalpindi. Study Design: Descriptive cross-sectional study. Place and Duration of Study: Tertiary care hospitals in Rawalpindi Pakistan, from Nov 2021 to Apr 2022. Methodology: A sample size of 120 women was calculated. Sampling technique was non-probability convenient sampling. The data collection tool consisted of demographic information, questions to assess awareness, perceptions and compliance towards mammography. Data were entered and analyzed in SPSS version 26. Results: The survey was administered to 120 women in tertiary care hospital. The study showed that majority of population was well-aware of breast cancer. Out of 120, 104(86%) women believed that new breast masses should be evaluated at clinics.According to 113(94%) women breast cancer can be cured and 95(79.2%) had belief that breast cancer can be prevented. Fortyfour (36.6%) women were non-complaint towards mammography having higher barrier scores. There was high significance of occupation (p<0.001), education (p<0.001) in terms of individual compliance towards mammography. Significant association was found among the participants who were compliant towards mammography with respect to occupation (p<0.001) and education (p<0.001). Conclusion: Most of women were well-aware of breast cancer and were more likely to participate in breast health activities.Majority had good perception regarding breast cancer and sufficient knowledge. Lesser women were non-complaint having barriers towards mammography.

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The first BGICC consensus and recommendations for breast cancer awareness, early detection and risk reduction in low‐ and middle‐income countries and the MENA region

Cited by 10 publications

References 33 publications

Promocija zdravlja i komponente socijalnog marketinga u funkciji ranog otkrivanja raka dojke

Promocija zdravlja i komponente socijalnog marketinga u funkciji ranog otkrivanja raka dojke

The profiles of miR-4510 expression level in breast cancer

Awareness Regarding Breast Cancer, Perceptions and Compliance towards Mammography among Women Visiting Tertiary Care Hospitals in Rawalpindi

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