The First Step for National Tuberculosis Laboratory Surveillance; Ankara, 2011

Sezen, Figen; Albayrak, Nurhan; Özkara, Şeref; Karagöz, Alper; ALP, Alpaslan; Agca, Filiz Duyar; Suer, Asiye Inan

doi:10.5578/mb.9170

Cited by 7 publications

(3 citation statements)

References 11 publications

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“…'nın (4) yaptığı çalışmada ÇİD MTK suş sayısı 10 (% 4.8) olarak bulunmuştur. Tüberküloz Laboratuvar Sürveyans Ağı (TuLSA) grubu tarafından 2011 yılında yapılmış olan ve ülke-mizdeki birçok tüberküloz laboratuvarı ve verem savaş dispanserinin katıldığı çok merkezli çalışmada ise tespit edilen ÇİD MTK oranı % 3.5'tir (15) .…”

Section: Discussionunclassified

Sensitivity Ratios in Mycobacterium tuberculosis Complex Isolates

Öncel¹,

Karahasan²,

İlki³

et al. 2019

Ankem Derg

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Tüberküloz tüm dünyada ciddi bir halk sağlığı sorunu olarak halen önemini korumakta, özellikle dirençli suşlarla infekte olan hastalarda ciddi morbidite ve mortaliteye neden olmaktadır. Bu çalışmanın amacı klinik örneklerden izole edilmiş Mycobacterium tuberculosis kompleksi (MTK) suşlarının primer anti-tüberküloz ilaçları olan izoniyazid (INH), rifampisin (RIF), streptomisin (SM) ve etambutole (ETM) karşı geliştirdikleri direnç oranlarının tespit edilmesidir.

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Section: Discussionunclassified

Sensitivity Ratios in Mycobacterium tuberculosis Complex Isolates

Öncel¹,

Karahasan²,

İlki³

et al. 2019

Ankem Derg

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“…Several studies in Turkey have found similar results, finding ST53 the most prevalent type with rates differing between 27.2% and 16.1%, followed by ST41 (8)(9)(10)(11). However, in three different studies on strains isolated in Ankara and East Anatolia, ST41 was found as the most prevalent type with rates between 21% and 47.5%, followed by ST53 (12)(13)(14). The unexpectedly marked difference between the rates of ST53, ST41, and ST284 in two distinct studies from Ankara may be due to the study by Kisa et al (11) that may represent Turkey more reliably because of military recruitment obligations.…”

Section: Discussionmentioning

confidence: 59%

Genotype distribution of Mycobacterium tuberculosis in theAegean Region and associated demographic factors

Çavuşoğlu¹,

Yılmaz²,

Durusoy³

et al. 2017

Turk J Med Sci

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IntroductionAccording to World Health Organization data, although there is a decreasing trend in tuberculosis (TB) incidence, prevalence, and mortality worldwide, the number of new TB cases in 2014 was estimated as 9.6 million, including 5.4 million men, 3.2 million women, and 1 million children. In 2014, 1.5 million individuals died because of TB (1).The incidence of TB in Turkey has dropped from 52.2/100,000 in 1980 to 26/100,000 in 2005 and 18/100,000 in 2014 (1-3). In total, 15,679 new TB cases, consisting of 59% pulmonary, 37% extrapulmonary, and 4% simultaneous pulmonary and extrapulmonary TB cases, were reported in Turkey in 2011. Among these cases, 59% of patients were males and 41% were females, and the highest incidence rates for both sexes were over the age of 65 years (2).The Aegean Region is the second-ranking region in Turkey according to the Human Development Index and population density and it hosts 1/8 of Turkey's population. İzmir is the largest city of the region and Turkey's third largest city with its 4,113,000 inhabitants receiving internal migration both from inside and outside the region (4,5). TB incidence in İzmir is lower than overall in Turkey: 17.7/100,000 in 2011. In İzmir, a total of 700 cases were reported in 2011 and 61% of the cases were pulmonary, 33% extrapulmonary, and 6% both pulmonary and extrapulmonary. Among the patients, 64% were male and 36% were female (2).The aims of this study were to determine the genotypes of Mycobacterium tuberculosis strains isolated in Ege University Medical School's hospital in 2009-2014; to Background/aim: The Aegean Region is the second-ranking region in Turkey according to the Human Development Index and population density and it hosts 1/8 of Turkey's population. İzmir is the largest city of the region, receiving internal migration both from inside and outside the region. The tuberculosis incidence in İzmir is lower than overall in Turkey: 17.7/100,000 in 2011. Our aims were to determine genotypes of Mycobacterium tuberculosis isolates; to explore possible associations between genotypes with casedemographic data, clinical presentation, and antimicrobial susceptibility patterns; and to determine variations in genotype distribution of strains isolated in

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“…For the surveillance in Ankara, another study was carried out by Sezen et al (20). They detected the resistance to INH as 3,8%, to RIF 0,9%, to SM 3,8%, EMB to 0,5% (20).…”

Section: Resultsmentioning

confidence: 99%

Resistance Rates of Mycobacterium Tuberculosis Complex Isola - Tes Obtained From Clinical Samples to Major Antituberculous Drugs: A Study in Edirne, Turkey

Öner¹,

Özdemir²,

Elmacı³

et al. 2018

tmsj

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Aims: The aim of this study is to reveal the rates of the Mycobacterium tuberculosis complex resistance to major antituberculous drugs (streptomycin, isoniazid, rifampicin, ethambutol) by the evaluation of the specimens that are sent to Trakya University Hospital Microbiology Laboratory. Methods: In this study, laboratory data of the cases that were pre-diagnosed with tuberculosis between 11/02/2016 and 31/12/2017 were scanned retrospectively. To compare the annual data descriptive statistics as arithmetic mean, numbers and percentages were used. Results: Out of 4752 samples, 133 (2.79%) were culture positive. 120 isolates were identified as Mycobacterium tuberculosis complex, while other 13 were defined as Mycobacterium other than tuberculosis. Antimycobacterial susceptibility tests showed that 9 (7.5%) isolates were resistant to streptomycin, 10 (8.33%) isolates to isoniazid, 4 (3.33%) isolates to rifampicin, 4 (3.33) isolates to ethambutol. 5 (4.16%) isolates were multidrug resistant. Conclusion: Antituberculous drug resistance is still a threat for an effective treatment of tuberculosis and streptomycin resistance has increased. However, it is also pointed out that presence of Mycobacterium other than tuberculosis in isolates has increased.

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The First Step for National Tuberculosis Laboratory Surveillance; Ankara, 2011

Cited by 7 publications

References 11 publications

Sensitivity Ratios in Mycobacterium tuberculosis Complex Isolates

Sensitivity Ratios in Mycobacterium tuberculosis Complex Isolates

Genotype distribution of Mycobacterium tuberculosis in theAegean Region and associated demographic factors

Resistance Rates of Mycobacterium Tuberculosis Complex Isola - Tes Obtained From Clinical Samples to Major Antituberculous Drugs: A Study in Edirne, Turkey

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