The Flexible Arrayed Non-Enzymatic CZO Glucose Sensor Utilizing Silver Nanowires and Nafion

Chou, Jung-Chuan; Huang, Yuhao; Lai, Chih-Hsien; Nien, Yu–Hsun; Kuo, Po-Yu; Kang, Zhi-Xuan; Lee, Kun-Tse

doi:10.1109/tim.2021.3099572

Cited by 9 publications

(2 citation statements)

References 45 publications

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“…After the reaction stabilized, we dropped 250 μL of 30mg/dL urea solution at 30 seconds and observed the response voltage change. The formula for response time is given as follows [41]:…”

Section: Response Time Of Urea Biosensormentioning

confidence: 99%

Design and Fabrication of PDMS Microfluidic Device Combined With Urea Biosensor for Dynamic and Static Measurements

Kuo

Wang

Hsu

et al. 2023

IEEE J. Electron Devices Soc.

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In this study, a more efficient, convenient, and cost-effective way was proposed to design and fabricate a polydimethylsiloxane (PDMS) microfluidic device using 3D printing and transfer techniques. Typically, sensor measurements can only be conducted by immersing the sensor in a solution under static conditions. However, in this study, a newly designed microfluidic device combined with a microfluidic system enables dynamic measurements with sensors. By controlling the flow and temperature of the test liquid, the physiological environment of the human body under various conditions can be simulated, resulting in more accurate and realistic data. During the dynamic condition, an average sensitivity of 6.396 mV/(mg/dL) and linearity of 0.999 were obtained at a flow rate of 75.0 μL/min. When the temperature was at 37 • C, the biosensor achieved an average sensitivity of 4.381 mV/(mg/dL) and a linearity of 0.999. The dynamic response time was 7 seconds, and the drift rate was 1.47 mV/hr. The experimental results obtained under dynamic conditions showed a significant improvement in the sensing characteristics of the urea biosensor compared with the results obtained under static conditions.

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“…After the reaction stabilized, we dropped 250 μL of 30mg/dL urea solution at 30 seconds and observed the response voltage change. The formula for response time is given as follows [41]:…”

Section: Response Time Of Urea Biosensormentioning

confidence: 99%

Design and Fabrication of PDMS Microfluidic Device Combined With Urea Biosensor for Dynamic and Static Measurements

Kuo

Wang

Hsu

et al. 2023

IEEE J. Electron Devices Soc.

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“…However, for strict clinical applications, it may still be necessary to increase the selectivity either by nanostructuring [15] or by using membranes such as Nafion. [63,64]…”

Section: Effect Of Interferentsmentioning

confidence: 99%

MBE Grown Vanadium Oxide Thin Films for Enhanced Non‐Enzymatic Glucose Sensing

Franceschini

Payo

Schouteden

et al. 2023

Adv Funct Materials

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In the search for non‐enzymatic alternatives to glucose oxidase, reliable and microchip‐compatible approaches to catalyst development are highly desirable. Herein, the electrochemical behavior of thin films of VOx deposited by molecular beam epitaxy (MBE) on glassy carbon electrodes is reported . A process of partial etching during polarization is observed. Thereafter, highly active and stable traces of VOx act as catalytic centers for glucose electrooxidation. A mechanistic description of the electrochemical process is proposed based on evidence provided by voltammetric measurements. The sensors are calibrated both with potentiometric and amperometric techniques, the former showing a wide linear range (1–10 mM), good sensitivity (14.93 ± 0.39 µA cm−2 × mM–1) and a limit of detection (0.32 m‐M). Unlike most metal oxides, it is shown that VOx on glassy carbon is capable of successfully oxidizing glucose at −0.4 V. Such a one‐of‐kind behavior can have important ramifications for energy‐efficient integrated electrochemical sensors and non‐enzymatic glucose sensing as a whole.

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Nickel-based catalysts for non-enzymatic electrochemical sensing of glucose: A review

Franceschini

Taurino

2022

Physics in Medicine

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The Flexible Arrayed Non-Enzymatic CZO Glucose Sensor Utilizing Silver Nanowires and Nafion

Cited by 9 publications

References 45 publications

Design and Fabrication of PDMS Microfluidic Device Combined With Urea Biosensor for Dynamic and Static Measurements

Design and Fabrication of PDMS Microfluidic Device Combined With Urea Biosensor for Dynamic and Static Measurements

MBE Grown Vanadium Oxide Thin Films for Enhanced Non‐Enzymatic Glucose Sensing

Nickel-based catalysts for non-enzymatic electrochemical sensing of glucose: A review

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