The Frontal Assessment Battery (FAB) in Parkinson’s disease and correlations with formal measures of executive functioning

Lima, César F.; Meireles, Laura; Fonseca, R.; Castro, São Luís; Garrett, Carolina

doi:10.1007/s00415-008-0024-6

Cited by 145 publications

(137 citation statements)

References 23 publications

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“…Several validation studies have shown that the FAB is sensitive to detecting frontal executive impairment compared with more extensive neuropsychological tests. However, most of these studies were performed on patients with dementia, 20,40,41 and the FAB has not been validated in an OHCA population.…”

Section: Discussionmentioning

confidence: 99%

Cognitive Function in Survivors of Out-of-Hospital Cardiac Arrest After Target Temperature Management at 33°C Versus 36°C

et al. 2015

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Background— Target temperature management is recommended as a neuroprotective strategy after out-of-hospital cardiac arrest. Potential effects of different target temperatures on cognitive impairment commonly described in survivors have not been investigated sufficiently. The primary aim of this study was to evaluate whether a target temperature of 33°C compared with 36°C was favorable for cognitive function; the secondary aim was to describe cognitive impairment in cardiac arrest survivors in general. Methods and Results— Study sites included 652 cardiac arrest survivors originally randomized and stratified for site to temperature control at 33°C or 36°C within the Target Temperature Management trial. Survival until 180 days after the arrest was 52% (33°C, n=178/328; 36°C, n=164/324). Survivors were invited to a face-to-face follow-up, and 287 cardiac arrest survivors (33°C, n=148/36°C, n=139) were assessed with tests for memory (Rivermead Behavioural Memory Test), executive functions (Frontal Assessment Battery), and attention/mental speed (Symbol Digit Modalities Test). A control group of 119 matched patients hospitalized for acute ST-segment–elevation myocardial infarction without cardiac arrest performed the same assessments. Half of the cardiac arrest survivors had cognitive impairment, which was mostly mild. Cognitive outcome did not differ ( P >0.30) between the 2 temperature groups (33°C/36°C). Compared with control subjects with ST-segment–elevation myocardial infarction, attention/mental speed was more affected among cardiac arrest patients, but results for memory and executive functioning were similar. Conclusions— Cognitive function was comparable in survivors of out-of-hospital cardiac arrest when a temperature of 33°C and 36°C was targeted. Cognitive impairment detected in cardiac arrest survivors was also common in matched control subjects with ST-segment–elevation myocardial infarction not having had a cardiac arrest. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT01946932.

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Section: Discussionmentioning

confidence: 99%

Cognitive Function in Survivors of Out-of-Hospital Cardiac Arrest After Target Temperature Management at 33°C Versus 36°C

et al. 2015

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“…The Frontal Assessment Battery (FAB; Dubois, Slachevsky, Litvan, & Pillon, 2000 ) is an executive screening test that, over the last years, has become widely used in neurological research (Guedj et al, 2008 ;Lima, Meireles, Fonseca, Castro, & Garrett, 2008 ;Oguro et al, 2006 ;Santangelo et al, 2009 ;Yoshida et al, 2009 ). It consists of six subtests assessing conceptualization, cognitive fl exibility, motor programming, sensitivity to interference, motor inhibitory control, and prehension behavior.…”

Section: Introductionmentioning

confidence: 99%

INECO Frontal Screening (IFS): A brief, sensitive, and specific tool to assess executive functions in dementia – ERRATUM

Torralva¹,

Roca²,

Gleichgerrcht³

et al. 2009

J Int Neuropsychol Soc

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“…Recently, normative FAB scores for Portuguese subjects have been proposed. The authors evaluated 122 healthy controls using an adapted version of the Brazilian one of the FAB 5 . The aim of the present study was to evaluate the performance of a Brazilian sample of healthy controls on the FAB, correlating their scores to age, gender, schooling and those from the Mini-Mental State Examination (MMSE), as well as to present scores according to the educational level.…”

mentioning

confidence: 99%

Frontal assessment battery in a Brazilian sample of healthy controls: normative data

Beato

Amaral-Carvalho

Guimarães

et al. 2012

Arq. Neuro-Psiquiatr.

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OBJECTIVE: To show data on the performance of healthy subjects in the Frontal Assessment Battery (FAB), correlating with gender, age, education, and scores in the Mini-Mental State Examination (MMSE). METHODS: Two hundred and seventy-five healthy individuals with mean age of 66.4±10.6 years-old were evaluated. Mean total FAB scores were established according to the educational level. RESULTS: Mean total FAB scores according to the educational level were 10.9±2.3, for one to three years; 12.8±2.7, for four to seven years; 13.8±2.2, for eight to 11 years; and 15.3±2.3, for 12 or more years. Total FAB scores correlated significantly with education (r=0.47; p<0.0001) and MMSE scores (r=0.39; p<0.0001). No correlation emerged between FAB scores, age, and gender. CONCLUSION: In this group of healthy subjects, the Brazilian version of the FAB proved to be influenced by the education level, but not by age and gender.

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The Frontal Assessment Battery (FAB) in Parkinson’s disease and correlations with formal measures of executive functioning

Abstract: The FAB is a useful tool for the screening of executive dysfunction in PD, showing good discriminant and concurrent validities. Normative data provided for the Portuguese version of this test improve the accuracy and confidence in the clinical use of the FAB.

Cited by 145 publications

References 23 publications

Cognitive Function in Survivors of Out-of-Hospital Cardiac Arrest After Target Temperature Management at 33°C Versus 36°C

Cognitive Function in Survivors of Out-of-Hospital Cardiac Arrest After Target Temperature Management at 33°C Versus 36°C

INECO Frontal Screening (IFS): A brief, sensitive, and specific tool to assess executive functions in dementia – ERRATUM

Frontal assessment battery in a Brazilian sample of healthy controls: normative data

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