The Functional Dysphagia Scale Is a Useful Tool for Predicting Aspiration Pneumonia in Patients With Parkinson Disease

Lee, Jong Hwa; Lee, Kyeong Woo; Kim, Sang Beom; Lee, Sook Jeong; Chun, Sang Myung; Jung, Sung Moon

doi:10.5535/arm.2016.40.3.440

Cited by 28 publications

(25 citation statements)

References 28 publications

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“…Lee JH, et al [ 13 ] and Argolo N, et al [ 14 ] examined VFSS parameters in patients with PD. In their studies, pharyngeal residue, pharyngeal transit time, or piecemeal deglutition are specific predictors of aspiration in PD, and also in our study, all the parameters of pharyngeal phase, including these three parameters, were significantly associated with the development of aspiration pneumonia ( Table 2 ).…”

Section: Discussionmentioning

confidence: 99%

Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson’s disease

et al. 2018

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IntroductionA number of video-fluoroscopic swallowing study (VFSS) abnormalities have been reported in patients with Parkinson’s disease (PD). However, the most crucial finding of subsequent aspiration pneumonia has not been validated fully. We conducted a retrospective and case-control study to determine the clinically significant VFSS findings in this population, and to propose a practical scale for predicting aspiration pneumonia in patients with PD.MethodsWe enrolled 184 PD patients who underwent VFSS because of suspected dysphagia. The patients who developed aspiration pneumonia within six months of the VFSS were assigned as cases and the patients without aspiration pneumonia at six months were designated as controls. Logistic regression analysis was performed to determine the prognostic VFSS features based on the data of swallowing 3 mL of jelly, which were used to make a PD VFSS scale (PDVFS). The validity of the new PDVFS was evaluated by ROC analysis. Additionally, we used the survival time analysis to compare time to death between groups, stratified by the PDVFS score.ResultsTwenty-five patients developed aspiration pneumonia. Among the previously-proposed VFSS features, mastication, lingual motility prior to transfer, aspiration, and total swallow time were identified as significant prognostic factors. We combined these factors to form the PDVFS. The PDVFS score ranges from 0 to 12, with 12 being the worst. ROC analysis revealed 92% sensitivity and 82% specificity at a cutoff point of 3. The higher PDVFS group showed shorter time-to-death than the lower PDVFS group (log rank P = 0.001).ConclusionOur newly developed VFSS severity scale (based on jelly swallowing) for patients with PD was easy to rate and could predict subsequent aspiration pneumonia and poor prognosis in patients with PD.

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Section: Discussionmentioning

confidence: 99%

Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson’s disease

et al. 2018

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“…One study showed a link between treated dental caries and a decreased risk of pneumonia among PD patients, which suggests that aspiration pneumonia plays an important role in this group of patients [ 12 ]. The other study demonstrated that the functional dysphagia scale could be used to predict aspiration pneumonia in PD patients [ 13 ]. Furthermore, ventilatory dysfunction including lung volume, respiratory muscle weakness, and sleep breathing disorders were all affected in PD patients [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

Manifestations and Outcomes of Patients with Parkinson’s Disease and Serious Infection in the Emergency Department

Kung

Chen

et al. 2018

BioMed Research International

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Background Several comorbidities contribute to an increased risk of infections in Parkinson's disease (PD) as the disease progresses. However, few studies have examined the correlation between sepsis and PD. Aim The aim of this study is to disclose the presentation and outcome of serious infection in patients with PD in the emergency department. Methods This retrospective cohort study enrolled patients with PD who had serious infection and were admitted to the emergency department between January 2007 and December 2013. For clinical comparison, we compared the clinical features, laboratory data, and outcomes with those of age- and sex-matched patients who had serious infection but not PD. Results There were a total of 1,200 episodes of infected PD patients and 2,400 age- and sex-matched infected patients without PD as disease controls. PD patients had fewer comorbidities and lower severity of infectious disease but longer hospital stays than control group patients. The incidences of respiratory tract and urinary tract infections were higher in PD patients. The levels of inflammatory and organ dysfunction biomarkers in PD were lower and compatible with the severity of infectious disease. A total of 86 (7.2%) infected PD patients died during the 28-day admission compared to 339 (14.1%) in non-PD patients. Serum C-reactive protein, bandemia, and lactate could be used to predict mortality in infected PD patients. Conclusions In infected patients with PD, respiratory and urinary tract infections were the two most common infectious sources. Empiric therapy based on experience could treat both respiratory and urinary tract infections. Early diagnosis and treatment are essential for survival.

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“…There was no scale for the “recommended” criteria that is proven to be valid, reliable, and sensitive in clinical studies. A recent study showed that the functional dysphagia scale (FDS) and the Schwab and England activities of daily living (S-E ADL) scale can effectively predict the occurrence of aspiration pneumonia in patients with PD [42]. Clinical scales of nonmotor symptoms relating to dysphagia for patients with PD are summarized in Table 2 [39].…”

Section: Parkinson’s Diseasementioning

confidence: 99%

Oro-Pharyngeal Dysphagia in Parkinson’s Disease and Related Movement Disorders

Kwon¹,

Lee

2019

JMD

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Oro-pharyngeal dysphagia is a common symptom in patients with Parkinson’s disease (PD) and related disorders, even in their early stage of diseases. Dysphagia in these patients has been underdiagnosed, probably due to poor the self-awareness of the conditions and the underuse of validated tools and objective instruments for assessment. The early detection and intervention of dysphagia are closely related to improving the quality of life and decreasing the mortality rate in these patients. The purpose of this paper is to give an overview of the characteristics of dysphagia, including the epidemiology, pathophysiology, and clinical symptomatology, in patients with PD compared with other parkinsonian disorders and movement disorders. The management of dysphagia and future research directions related to these disorders are also discussed.

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The Functional Dysphagia Scale Is a Useful Tool for Predicting Aspiration Pneumonia in Patients With Parkinson Disease

Cited by 28 publications

References 28 publications

Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson’s disease

Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson’s disease

Manifestations and Outcomes of Patients with Parkinson’s Disease and Serious Infection in the Emergency Department

Oro-Pharyngeal Dysphagia in Parkinson’s Disease and Related Movement Disorders

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