The GEDNAP (German DNA profiling group) blind trial concept

Abstract

This paper presents a review of the organisation and background of blind trial systems in general and in particular the system developed in Münster originally for the German Society of Forensic Medicine. This system, known as GEDNAP (German DNA profiling group), has now evolved into a multinational DNA blind trial open to all laboratories involved in paternity and forensic DNA testing.

Differential DNA extraction of challenging simulated sexual-assault samples: a Swiss collaborative study

“…Nonetheless, each laboratory works with its own validated protocols, whose efficiency may fluctuate. National and international proficiency-testing programs, such as the German DNA Profiling Group (GEDNAP) [24], contribute to the consistency across laboratories. However, challenging samples, such as those analyzed in the present study, are seldom considered in these programs.…”

Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on quality control of autosomal Short Tandem Repeat allele frequency databasing (STRidER)

“…Numerous guidance papers on forensic STR typing and interpretation were published (e.g., [4][5][6][7][8][9][10]) that highlight the importance of internal and external quality control (QC). Community based (e.g., [11][12][13][14]) and commercial (see example in [15]) proficiency testing programs that are powerful in highlighting problems with the analytical procedure and interpretational issues of STR typing in a routine forensic laboratory have been implemented. However, published datasets that form the basis for statistical evaluation in forensic genetics are not yet part of any external standardized quality control program -despite a growing number of contributions.…”

A new miniSTR heptaplex system for genetic fingerprinting of ancient DNA from archaeological human bone

“…The GEDNAP blind trials organized by the Stain Commission of the DGRM (Deutsche Gesellschaft für Rechtsmedizin/German Society for Legal Medicine) are proficiency tests for quality assurance in laboratories producing results for the legal system (Rand et al, 2002). Each participating laboratory has to type two sets of reference samples and stains per year.…”