2024
DOI: 10.3389/fpsyt.2024.1414776
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The genetic association between bipolar disorder and dementia: a qualitative review

Hirofumi Hirakawa,
Takeshi Terao

Abstract: Bipolar disorder is a chronic disorder characterized by fluctuations in mood state and energy and recurrent episodes of mania/hypomania and depression. Bipolar disorder may be regarded as a neuro-progressive disorder in which repeated mood episodes may lead to cognitive decline and dementia development. In the current review, we employed genome-wide association studies to comprehensively investigate the genetic variants associated with bipolar disorder and dementia. Thirty-nine published manuscripts were ident… Show more

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