The Genome Assembly and Annotation of the Southern Elephant Seal Mirounga leonina

Kim, Bo Mi; Lee, Yoon Jin; Kim, Jeong Hoon; Kim, Jin Hyoung; Kang, Seunghyun; Jo, Euna; Lee, Seung-Jae; Lee, Jun Hyuck; Min, Young; Park, Hyun

doi:10.3390/genes11020160

Cited by 3 publications

(2 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Here, we present a highly contiguous genome for the tayra ( Eira barbara ). Contiguity of the assembly and its gene completeness are similar to or higher than those of other carnivoran species using the same sequencing approach (Armstrong et al, 2019; Etherington et al, 2020; Kim et al, 2020), confirming the utility of linked reads for assembly of mammal genomes.…”

Section: Discussionmentioning

confidence: 56%

Multiple types of genomic variation contribute to adaptive traits in the mustelid subfamily Guloninae

et al. 2022

View full text Add to dashboard Cite

Species of the mustelid subfamily Guloninae inhabit diverse habitats on multiple continents, and occupy a variety of ecological niches. They differ in feeding ecologies, reproductive strategies and morphological adaptations. To identify candidate loci associated with adaptations to their respective environments, we generated a de novo assembly of the tayra (Eira barbara), the earliest diverging species in the subfamily, and compared this with the genomes available for the wolverine (Gulo gulo) and the sable (Martes zibellina). Our comparative genomic analyses included searching for signs of positive selection, examining changes in gene family sizes and searching for species‐specific structural variants. Among candidate loci associated with phenotypic traits, we observed many related to diet, body condition and reproduction. For example, for the tayra, which has an atypical gulonine reproductive strategy of aseasonal breeding, we observed species‐specific changes in many pregnancy‐related genes. For the wolverine, a circumpolar hypercarnivore that must cope with seasonal food scarcity, we observed many changes in genes associated with diet and body condition. All types of genomic variation examined (single nucleotide polymorphisms, gene family expansions, structural variants) contributed substantially to the identification of candidate loci. This argues strongly for consideration of variation other than single nucleotide polymorphisms in comparative genomics studies aiming to identify loci of adaptive significance.

show abstract

Section: Discussionmentioning

confidence: 56%

Multiple types of genomic variation contribute to adaptive traits in the mustelid subfamily Guloninae

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Here, we present a highly contiguous genome for the tayra (Eira barbara). Contiguity of the assembly and its gene completeness are similar to or higher than those of other carnivoran species using the same sequencing approach (Armstrong et al, 2019, Etherington et al, 2020, Kim et al, 2020, confirming the utility of linked-reads for assembly of mammal genomes.…”

Section: Discussionsupporting

confidence: 52%

Multiple types of genomic variation contribute to adaptive traits in the mustelid subfamily Guloninae

Derežanin

Blažytė

Dobrynin

et al. 2021

Preprint

View full text Add to dashboard Cite

Species of the mustelid subfamily Guloninae inhabit diverse habitats on multiple continents, and occupy a variety of ecological niches. They differ in feeding ecologies, reproductive strategies and morphological adaptations. To identify candidate loci associated with adaptations to their respective environments, we generated a de novo assembly of the tayra (Eira barbara), the earliest diverging species in the subfamily, and compared this with the genomes available for the wolverine (Gulo gulo) and the sable (Martes zibellina). Our comparative genomic analyses included searching for signs of positive selection, examining changes in gene family sizes, as well as searching for species-specific structural variants (SVs). Among candidate loci that appear to be associated with phenotypic traits, we observed many genes related to diet, body condition and reproduction. For the tayra, which has an atypical gulonine reproductive strategy of aseasonal breeding, we observe species-specific changes in many pregnancy-related genes. For the wolverine, a circumpolar hypercarnivore that must cope with seasonal food scarcity, we observed many specific changes in genes associated with diet and body condition. Despite restricting some of our analyses to single-copy orthologs present in all three study species, we observed many candidate loci that may be linked to species traits related to environment-specific challenges in their respective habitats.

show abstract

Excellent Anti-lung Cancer Activity of <i>Populus nigra</i> and Phylogenetic Analysis

Gao

Jiang

et al. 2021

J. Oleo Sci.

View full text Add to dashboard Cite

IntroductionLung cancer is one of the malignant tumors with the fastest increase in morbidity and mortality and the greatest threat to human health and life. Therefore, the incidence and death of lung cancer have now become a major cause of death for urban residents in our country 1) . Traditionally, the cancer treatment commonly used in clinic were surgery, radiation, chemotherapy, and immunotherapy, which were targeted on the highly proliferation of tumor cells, but which could cause many adverse reactions and the production of cancer-resistance 2) . Among the various effective anti-cancer drugs currently used in clinical practice, more than half of the drugs are originally derived from natural products. Statistics show that plant-derived anticancer drugs can account for more than 50％ of the anticancer drugs used in hospitals, and paclitaxel ranks first among various anti-cancer drugs. Populus nigra is reported exhibiting multiple pharmacological activities, such as anti-inflammatory and anticoagulant activity 3−6) . However, there is no solid record and reliable experimental data

show abstract

The Genome Assembly and Annotation of the Southern Elephant Seal Mirounga leonina

Cited by 3 publications

References 30 publications

Multiple types of genomic variation contribute to adaptive traits in the mustelid subfamily Guloninae

Multiple types of genomic variation contribute to adaptive traits in the mustelid subfamily Guloninae

Multiple types of genomic variation contribute to adaptive traits in the mustelid subfamily Guloninae

Excellent Anti-lung Cancer Activity of <i>Populus nigra</i> and Phylogenetic Analysis

Contact Info

Product

Resources

About