The Genus Serratia

Grimont, Francine; Grimont, Patrick A. D.

doi:10.1007/0-387-30746-x_11

Cited by 207 publications

(219 citation statements)

References 132 publications

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“…is member of the Enterobacteriaceae family (facultative anaerobic, Gram-negative, cytochrome oxidase negative and catalase positive). In general, Serratia marcescens is reported most frequently as a pathogen of insectary-reared insects (Krieg 1987, Grimont & Grimont 1992. S. marcescens was identified in intestinal tube of Lutzomyia longipalpis, and was more abundant in sandflies fed on blood and sugar than the ones fed only on blood (Oliveira et al 2001).…”

Section: Discussionmentioning

confidence: 99%

First isolation of microorganisms from the gut diverticulum of Aedes aegypti (Diptera: Culicidae): new perspectives for an insect-bacteria association

Gusmão

Santos

Marini

et al. 2007

Mem. Inst. Oswaldo Cruz

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We show for the first time that the ventral diverticulum of the mosquito gut (impermeable sugar storage organ) harbors microorganisms. The gut diverticulum from newly emerged and non-fedAedes aegypti (Diptera: Culicidae, Aedini) is the main urban vector for the human diseases yellow fever and dengue fever (Nasci & Miller 1996). The vector control, mainly by insecticide application and elimination of oviposition sites, has been used as the best solution to decrease the diseases incidence. Explore new strategies for blocking the insect transmitted diseases such as dengue fever is urgent in Tropical countries (Sperança & Capurro 2007). Microorganisms associated with the insect may have an important role for human infectious diseases epidemiology. Once a key role bacterium is discovered, it may be modified in order to affect the pathogen development and, consequently, the disease transmission (Azambuja et al. 2005, Riehle & Jacobs-Lorena 2005.The alimentary canal of the mosquito is composed by the foregut, midgut and hindgut. The foregut is involved primarily with ingestion, conduction and storage of food (Romoser 1996). In the alimentary canal of the mosquito three diverticula arise near the posterior end of the esophagus: two from the dorso-lateral and one from the ventral wall of the gut, all surrounded by a thin impermeable cuticle. The ventral diverticulum (VD), or crop, is large and may extend into the abdomen (Dapples & Lea 1974). Usually all three diverticula are filled with air bubbles and are used as food reservoirs (Thompson 1905, Consoli & Lourenço-de-Oliveira 1994. The sugar meal, such as floral nectar, is stored in the diverticula and passes slowly to the midgut, where it is digested (Thompson 1905).Microorganisms play important and often essential roles in the growth and development of many insect species. Despite the importance of these microbial associations with insects there are relatively few studies that elucidate their components and their roles in the interactions. Insects that rely on nutritionally poor diets tend to possess bacterial endosymbionts. Aphids, for example, which subsist solely on plant sap, harbor Buchnera spp., believed to provide amino acids and vitamins to their hosts (Douglas 1989). Blood is known to be severely deficient in essential B vitamins and some amino acids. Bloodsucking arthropods such as ticks, lice, bedbugs, reduviid bugs, and tsetse flies usually harbor symbiotic microorganisms (Buchner 1965). Symbiotic relationships have already been reported for blood feeding insects and some are very well established, as in the case of Rhodnius prolixus that maintains an association with the actinomycete bacteria Rhodococcus rhodnii (Dasch et al. 1984); and tsetse flies genus Glossina, which harbor three distinct symbiotic microorganisms: Wigglesworthia glossinidia, Sodalis glossinidius (commensal), and the parasitic microbe Wolbachia pipientis (Aksoy et al. 1997, Chen et al. 1999.Many key questions about bacteria within the mosquito's midgut remain largely unanswered, and ob...

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Section: Discussionmentioning

confidence: 99%

First isolation of microorganisms from the gut diverticulum of Aedes aegypti (Diptera: Culicidae): new perspectives for an insect-bacteria association

Gusmão

Santos

Marini

et al. 2007

Mem. Inst. Oswaldo Cruz

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“…As prey species, we used the bacterium S. marcescens ATCC 13880 [12]. The broad-host-range conjugative plasmid RP4 (incompatibility group P) [13] was transferred from Escherichia coli K-12 JE2571 [14] to S. marcescens.…”

Section: Materials and Methods (A) Strains And Culture Conditions (I) mentioning

confidence: 99%

Conjugation is necessary for a bacterial plasmid to survive under protozoan predation

et al. 2016

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Horizontal gene transfer by conjugative plasmids plays a critical role in the evolution of antibiotic resistance. Interactions between bacteria and other organisms can affect the persistence and spread of conjugative plasmids. Here we show that protozoan predation increased the persistence and spread of the antibiotic resistance plasmid RP4 in populations of the opportunist bacterial pathogen Serratia marcescens. A conjugation-defective mutant plasmid was unable to survive under predation, suggesting that conjugative transfer is required for plasmid persistence under the realistic condition of predation. These results indicate that multi-trophic interactions can affect the maintenance of conjugative plasmids with implications for bacterial evolution and the spread of antibiotic resistance genes.

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“…2) (Slater et al, 2003). Hyperpigmentation due to growth on PGM is widely reported in various S. marcescens strains (Grimont & Grimont, 1978) and so the Pho box may be present in the 59 regulatory region of all S. marcescens pig clusters. Indeed, a predicted Pho box has been identified 59 of pigA in Sma 274 (Fig.…”

Section: Differences In Pig Cluster Regulationmentioning

confidence: 99%

“…Some strains of Serratia marcescens cause nosocomial infections that are clinically problematic because multidrug resistance is widespread within the species (Stock et al, 2003;Traub, 2000). S. marcescens has been isolated from soil, water, plants and air (Grimont & Grimont, 1978). The ability of some S. marcescens strains to colonize a wide range of ecological niches has been linked to the production of a spectrum of extracellular products including chitinases, proteases, lipases, nucleases, bacteriocins, surfactants and wetting agents (Braun & Schmitz, 1980;Clegg & Allen, 1985;Hines et al, 1988;Matsuyama et al, 1995;Yanagida et al, 1986).…”

Section: Introductionmentioning

confidence: 99%

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The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation

et al. 2004

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The prodigiosin biosynthesis gene cluster (pig cluster) from two strains of Serratia (S. marcescens ATCC 274 and Serratia sp. ATCC 39006) has been cloned, sequenced and expressed in heterologous hosts. Sequence analysis of the respective pig clusters revealed 14 ORFs in S. marcescens ATCC 274 and 15 ORFs in Serratia sp. ATCC 39006. In each Serratia species, predicted gene products showed similarity to polyketide synthases (PKSs), non-ribosomal peptide synthases (NRPSs) and the Red proteins of Streptomyces coelicolor A3(2). Comparisons between the two Serratia pig clusters and the red cluster from Str. coelicolor A3(2) revealed some important differences. A modified scheme for the biosynthesis of prodigiosin, based on the pathway recently suggested for the synthesis of undecylprodigiosin, is proposed. The distribution of the pig cluster within several Serratia sp. isolates is demonstrated and the presence of cryptic clusters in some strains shown. The pig cluster of Serratia marcescens ATCC 274 is flanked by cueR and copA homologues and this configuration is demonstrated in several S. marcescens strains, whilst these genes are contiguous in strains lacking the pig cluster.

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The Genus Serratia

Cited by 207 publications

References 132 publications

First isolation of microorganisms from the gut diverticulum of Aedes aegypti (Diptera: Culicidae): new perspectives for an insect-bacteria association

First isolation of microorganisms from the gut diverticulum of Aedes aegypti (Diptera: Culicidae): new perspectives for an insect-bacteria association

Conjugation is necessary for a bacterial plasmid to survive under protozoan predation

The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation

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