The good bugs: the use of probiotics in pediatrics

Abstract

Purpose of review There is growing evidence encouraging the use of probiotics in many conditions in children. However, given the wide number of probiotics available and contradictory data in the literature, the health-care provider is often faced with uncertainness about whether or not to use probiotics and which one(s) to choose. We here review current hypotheses regarding the efficacy and safety of probiotics and evaluate the available data on the use of probiotics in most common diseases in children. Considering that probiotics have strain-specific effects, we will focus on individual probiotic strains rather than on probiotics in general. Recent findings Strain-specific efficacy was clearly demonstrated with Lactobacillus rhamnosus GG and Saccharomyces boulardii I-745 in the treatment of acute infectious diarrhea, Lactobacillus reuteri DSM 17938 in infantile colics, Lactobacillus rhamnosus GG, and VSL#3 in irritable bowel syndrome. In addition, encouraging results are seen for use of probiotics in necrotizing enterocolitis, food allergy, and nonalcoholic fatty liver disease. However, the data available for constipation are to be considered somewhat equivocal. Summary The clinical relevance of these findings indicates that healthcare providers need to take strain-specificity and disease specificity of probiotics into consideration when recommending probiotic for their patients.

Os Primeiros 1000 Dias Da Criança: Dicas De Um Pediatra

“…• Lactobacillus rhamnosus GG e VSL#3 (um mix de 7 probioticos), para síndrome do intestino irritável (Sansotta et al, 2019). Açucar.…”

Diagnosing and managing acute abdominal pain in children

“…Multiple studies have examined the use of probiotics in the treatment of gastroenteritis and have found a reduction in both the duration of diarrhea and relapse of the disease with use of Lactobacillus rhamnosus GG and Saccharomyces boulardii- I745 12…”

Whole genome sequence of Lactiplantibacillus plantarum strain HA9 isolated from conventional Iraqi cheese: First report

“…If a probiotic is shown to be the cause or is suspected of being the source of any invasive illness, knowledge of AMR patterns can help clinicians make treatment options. Additionally, understanding a microbe's AMR phenotype can aid in the development of innovative multi-component treatment regimens, which is crucial in light of the growing body of research supporting the simultaneous administration of probiotics and antibiotics [16][17][18].…”