The Great Mimicker—Tuberculosis Involving Prostate and Vertebrae Posing as Metastatic Prostate Carcinoma on FDG PET/CT

Abstract

A 65-year-old man underwent FDG PET/CT for evaluation of vertebral lesions, radiologically suspected to be metastases. The scan showed hypermetabolism in D8 to D9 vertebrae, retroperitoneal lymph nodes, and both the lobes of prostate. Transrectal ultrasound-guided biopsy of prostate was performed with suspicion of prostate malignancy. The biopsy revealed caseating granulomatous lesions in prostate suggestive of tuberculosis. Post antitubercular treatment patient showed excellent clinical response. Possibility of infective pathologies mimicking malignancy should be kept in mind while evaluating hypermetabolic foci seen on PET/CT. Although rare, tuberculosis of prostate needs consideration in differential diagnosis of FDG-avid foci seen in prostate.

Solitary Chest Wall Tuberculosis Mimicking a Malignancy Demonstrated on FDG PET/CT

“…4,5 However, FDG PET/CT image of tuberculosis in various sites may be misdiagnosed as malignant tumor. [6][7][8][9] Wang et al 10 reported a case of primary chest wall tuberculosis presenting as intense FDG uptake in the posterior pleural mass and adjacent muscle without rib involvement mimicking a malignancy. The patient in our case had simultaneous rib, muscle, and diaphragm invasion.…”

“…FDG PET/CT has vital value in evaluating total disease burden and treatment response in tuberculosis patients 4,5 . However, FDG PET/CT image of tuberculosis in various sites may be misdiagnosed as malignant tumor 6–9 . Wang et al 10 reported a case of primary chest wall tuberculosis presenting as intense FDG uptake in the posterior pleural mass and adjacent muscle without rib involvement mimicking a malignancy.…”

Spine Infections: The Role of Fluorodeoxyglucose Positron Emission Tomography (FDG PET) in the Context of the Actual Diagnosis Guideline

“…It has been shown that an acute osteoporotic fracture does not have any FDG uptake, and it can be expected that FDG-PET/CT allows the differentiation of osteoporotic vertebral fractures from pathological fractures due to malignancy or inflammatory disease, such as SD. It has to be reminded that FDG is not tumour or infective specific [ 69 , 70 ], and it could help in the identification of the right site for biopsy [ 71 , 72 ]. It has to be mentioned that FDG uptake was found in inflammatory and rheumatologic diseases [ 73 , 74 ], such as aseptic spondylodiscitis in a patient with HLA-B27 positive patient [ 74 ].…”

Application Effect of Bladder Function Training Combined with Kangaiping Pills on Permanent Bladder Stoma after Radical Prostatectomy

“…In recent years, with the acceleration of population aging in China, the harm of PC to Chinese men has been increasing [ 3 ]. With the continuous improvement of clinical surgical techniques in China, radical prostatectomy (RP) has become a common surgical approach in clinical practice, as well as a gold standard of surgery for PC [ 4 , 5 ]. Since RP has changed the normal urination, a permanent bladder stoma is necessary to protect renal function and maintain normal water-electrolyte metabolism and homeostasis.…”