The Herpes Simplex Virus in Infantile Eczema

Barrow, G. I.

doi:10.1136/bmj.1.4860.482

Cited by 6 publications

(1 citation statement)

References 16 publications

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“…At that point in time, it was already known that certain bacteria, such as Streptococcus pyogenes , Staphylococcus aureus and, obviously, C. diphtheriae , produced dangerous toxins; hence, it was important (and indeed recommended) to precisely identify the microorganism responsible for the OLP, as well as to provide the appropriate antimicrobial treatment for the disease. It also became apparent later on that the skin injury could facilitate colonization by additional bacteria, as well as viruses; the ubiquitous herpes simplex virus 1 (HSV1) was identified as one of the most common viruses colonizing the skin lesions, generating a condition known as eczema herpetiform or Kaposi varicelliform eruption (Barrow 1954 ).…”

Section: Bacteria Associated With Oral Lichen Planusmentioning

confidence: 99%

Oral lichen planus: a microbiologist point of view

2021

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Oral lichen planus (OLP) is a chronic disease of uncertain etiology, although it is generally considered as an immune-mediated disease that affects the mucous membranes and even the skin and nails. Over the years, this disease was attributed to a variety of causes, including different types of microorganisms. This review analyzes the present state of the art of the disease, from a microbiological point of view, while considering whether or not the possibility of a microbial origin for the disease can be supported. From the evidence presented here, OLP should be considered an immunological disease, as it was initially proposed, as opposed to an illness of microbiological origin. The different microorganisms so far described as putative disease-causing agents do not fulfill Koch’s postulates; they are, actually, not the cause, but a result of the disease that provides the right circumstances for microbial colonization. This means that, at this stage, and unless new data becomes available, no microorganism can be envisaged as the causative agent of lichen planus.

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Section: Bacteria Associated With Oral Lichen Planusmentioning

confidence: 99%