The hormone-sensitive lipase C-60G polymorphism is correlated with recurrent spontaneous abortion in women with polycystic ovary syndrome

Eivazi, Samira; Kheirollahi, Asma; Vatannejad, Akram; Borumandnia, Nasrin; Habibi, Behnam; Shapourizadeh, Somayeh; Fouani, Fatima Zahraa; Ansaripour, Soheila; Eivazi, Sadegh; Zandieh, Zahra

doi:10.1016/j.genrep.2023.101788

Cited by 2 publications

(1 citation statement)

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“…The commonly medicine for routine treatment are progesterone and Gushen Antai pills. Progesterone has a significant effect on women, and its use in the later stages of menstruation can promote the growth of glands in the patient's endometrium, cause uterine congestion, increase endometrial thickness, and prepare for fertilized egg implantation [6] . The use of it by pregnant women can effectively reduce the degree of uterine excitement during pregnancy, inhibit uterine activity, and ensure safe fetal growth in the body.…”

Section: Discussionmentioning

confidence: 99%

Study on the Efficacy of Aspirin Combined with Prednisone in the Treatment of Recurrent Spontaneous Abortion

2023

IJFM

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This paper aims to study the efficacy of aspirin combined with prednisone in the treatment of recurrent spontaneous abortion. This research officially started in March 2021 and ended in March 2022. 72 patients with recurrent spontaneous abortion admitted to our hospital during this research period were selected as the observation objects. They were divided into two groups according to the order of admission: a control group and an experimental group. The control group received routine treatment, and the experimental group received aspirin combined with prednisone treatment. The observation indicators and pregnancy outcomes of the two groups of patients were compared before and after treatment. There was no significant difference in coagulation function, IL-4, hormones, endometrial receptivity, and immune function indicators between the two groups of patients before treatment (P>0.05). After treatment, the research indicators of both groups of patients were effectively improved, but the improvement degree of the experimental group was significantly better than that of the control group, and the pregnancy outcome of the experimental group was better (P<0.05). Conclusion: Aspirin combined with prednisone treatment can achieve ideal efficacy in patients with recurrent spontaneous abortion, and is worthy of clinical promotion.

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Section: Discussionmentioning

confidence: 99%