The hot-wire concept: Towards a one-element thermal biosensor platform

Khorshid, Mehran; Sichani, Soroush Bakhshi; Cornelis, Peter; Wackers, Gideon; Wagner, Patrick

doi:10.1016/j.bios.2021.113043

Cited by 14 publications

(11 citation statements)

References 64 publications

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“…Although not well known, histamine can be detected quantitatively with thermometers when using the heat transfer method HTM (see Figure 13 a). The method relies on the fact that molecular-scale changes at an interface between a solid and a liquid measurably affect the efficiency of heat transfer from the solid to the liquid [ 225 ]. This can be expressed by the thermal resistance R th = ( T 1 − T 2 )/ P with T 1,2 being the temperatures at the chip backside and within the liquid (measured by thermocouples) and P the heating power [ 226 ].…”

Section: Biomimetic Sensors For Biogenic Amines Using Molecularly Imp...mentioning

confidence: 99%

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A Review on Bio- and Chemosensors for the Detection of Biogenic Amines in Food Safety Applications: The Status in 2022

Givanoudi

Heyndrickx

Depuydt

et al. 2023

Sensors

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This article provides an overview on the broad topic of biogenic amines (BAs) that are a persistent concern in the context of food quality and safety. They emerge mainly from the decomposition of amino acids in protein-rich food due to enzymes excreted by pathogenic bacteria that infect food under inappropriate storage conditions. While there are food authority regulations on the maximum allowed amounts of, e.g., histamine in fish, sensitive individuals can still suffer from medical conditions triggered by biogenic amines, and mass outbreaks of scombroid poisoning are reported regularly. We review first the classical techniques used for selective BA detection and quantification in analytical laboratories and focus then on sensor-based solutions aiming at on-site BA detection throughout the food chain. There are receptor-free chemosensors for BA detection and a vastly growing range of bio- and biomimetic sensors that employ receptors to enable selective molecular recognition. Regarding the receptors, we address enzymes, antibodies, molecularly imprinted polymers (MIPs), and aptamers as the most recent class of BA receptors. Furthermore, we address the underlying transducer technologies, including optical, electrochemical, mass-sensitive, and thermal-based sensing principles. The review concludes with an assessment on the persistent limitations of BA sensors, a technological forecast, and thoughts on short-term solutions.

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Section: Biomimetic Sensors For Biogenic Amines Using Molecularly Imp...mentioning

confidence: 99%

“…For the time being, there is still the drawback that HTM requires a temperature-stable environment, which can possibly be solved with the hot-wire technique of ref. [ 225 ].…”

Section: Biomimetic Sensors For Biogenic Amines Using Molecularly Imp...mentioning

confidence: 99%

A Review on Bio- and Chemosensors for the Detection of Biogenic Amines in Food Safety Applications: The Status in 2022

Givanoudi

Heyndrickx

Depuydt

et al. 2023

Sensors

Self Cite

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“…Thermal biosensors represent another interesting area of biosensor research and development. Biosensor platform based on change in the thermal interface conductance has been described recently ( Khorshid et al, 2021 ). This biosensor has been proposed to be used in various applications, including mutation analysis and aptamer-based analyte detection ( Khorshid et al, 2021 ).…”

Section: Biosensors For Point Mutation Detectionmentioning

confidence: 99%

Biosensors for Point Mutation Detection

Jiang

Juhas

et al. 2021

Front. Bioeng. Biotechnol.

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“…Biosensors are also compact and miniaturized devices that facilitate the advancement of portable sensing systems to monitor on-site effluents [ 29 ]. Bearing in mind the wide range of bio-recognition elements (including enzymatic, immunochemical, non-enzymatic receptor, whole-cell and DNA elements, and molecularly imprinted polymer (MIP)), the various types of biosensors can be classified as (i) electrochemical [ 30 ], (iii) piezoelectric [ 31 ], (ii) optical [ 32 ], and (iv) thermal biosensors [ 33 ] based on their working principles and transducing mechanisms [ 34 ], but the current review paper will cover the topics which are related to electrochemical biosensing. An electrochemical biosensor is based on the interactions between the immobilized bio-recognition element on its surface with binding molecules (the analyte of interest) and generating the changes in electrochemical properties, further translating into a meaningful electrical signal.…”

Section: Introductionmentioning

confidence: 99%

Recent Advancements in Electrochemical Biosensors for Monitoring the Water Quality

et al. 2022

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The release of chemicals and microorganisms from various sources, such as industry, agriculture, animal farming, wastewater treatment plants, and flooding, into water systems have caused water pollution in several parts of our world, endangering aquatic ecosystems and individual health. World Health Organization (WHO) has introduced strict standards for the maximum concentration limits for nutrients and chemicals in drinking water, surface water, and groundwater. It is crucial to have rapid, sensitive, and reliable analytical detection systems to monitor the pollution level regularly and meet the standard limit. Electrochemical biosensors are advantageous analytical devices or tools that convert a bio-signal by biorecognition elements into a significant electrical response. Thanks to the micro/nano fabrication techniques, electrochemical biosensors for sensitive, continuous, and real-time detection have attracted increasing attention among researchers and users worldwide. These devices take advantage of easy operation, portability, and rapid response. They can also be miniaturized, have a long-life span and a quick response time, and possess high sensitivity and selectivity and can be considered as portable biosensing assays. They are of special importance due to their great advantages such as affordability, simplicity, portability, and ability to detect at on-site. This review paper is concerned with the basic concepts of electrochemical biosensors and their applications in various water quality monitoring, such as inorganic chemicals, nutrients, microorganisms’ pollution, and organic pollutants, especially for developing real-time/online detection systems. The basic concepts of electrochemical biosensors, different surface modification techniques, bio-recognition elements (BRE), detection methods, and specific real-time water quality monitoring applications are reviewed thoroughly in this article.

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The hot-wire concept: Towards a one-element thermal biosensor platform

Cited by 14 publications

References 64 publications

A Review on Bio- and Chemosensors for the Detection of Biogenic Amines in Food Safety Applications: The Status in 2022

A Review on Bio- and Chemosensors for the Detection of Biogenic Amines in Food Safety Applications: The Status in 2022

Biosensors for Point Mutation Detection

Recent Advancements in Electrochemical Biosensors for Monitoring the Water Quality

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