The “Hub and Spoke” model: a pathway for urgent plasma exchange to treat patients with rodenticide ingestion induced acute liver failure in Tamil Nadu, India

Yellow phosphorus poisoning: is preemptive PLEX therapy feasible?

“…The referral chain starts with primary health centres for assessment and resuscitation and ends with district government medical college hospitals for plasma exchange (PLEX) for those who meet specific criteria so that PLEX potentially serves as a more cost-effective option compared to liver transplantation. 1 This indeed is a success of the academic community which generated the data and receptivity of the local government which facilitated implementation of the program as well as imposing a partial ban on the poison. It is quite reassuring to note that the hub and spoke model of PLEX therapy has reduced mortality.…”