The human health risk assessment of particulate air pollution (PM2.5 and PM10) in Romania

Bodor, Katalin; Szép, Róbert; Bodor, Zsolt

doi:10.1016/j.toxrep.2022.03.022

Cited by 43 publications

(32 citation statements)

References 38 publications

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“…PM, such as fossil fuel, diesel exhaust particles, and carbon black (CB) from incomplete combustion from diesel vehicles and cars, are the main components that make up urban air pollution. Fine PM air pollution poses an even greater threat to human health than dust storms ( 14 ). Outside of the human nose, particles with a particle size of 10 µm or more will be prevented.…”

Section: Discussionmentioning

confidence: 99%

Effects of short-term waterfall forest aerosol air exposure on rat lung proteomics

Zhu¹,

Zhao²,

Zhu³

et al. 2022

Ann Transl Med

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Background: Chronic exposure to airborne microparticles has been shown to increase the incidence of several chronic diseases. Previous studies have found that waterfall forest aerosols contribute to a diminished immune stress response in patients with asthma. However, the specific effects of short-term waterfall forest aerosol exposure on lung proteins have not been fully elucidated.Methods: This study used liquid chromatography-tandem mass spectrometry (LC-MS) to analyze changes in protein expression in the lungs of rats exposed to short-term waterfall forest aerosol environments. Specific protein markers were identified using bioconductivity analysis screening and validated using immunohistochemistry.Results: Waterfall forest aerosol environment exposure on day 5 downregulated the expression of the classical inflammatory pathway nuclear factor κB (NF-κB) signaling pathway. As the waterfall forest aerosol environment increased due to the duration of exposure, it was involved in oxidative phosphorylation and then hormone signaling in lung cells from the very beginning. In contrast, at day 15 of exposure, there is an effect on the regulation of the immune-related high-affinity IgE receptor pathway. In addition, iron-sulfur Rieske protein (Uqcrfs1), mitochondrial Tu translation elongation factor (Tufm) and ribosomal protein L4 (Rpl4) were identified as possible bioindicators for the evaluation of air quality.Conclusions: These results provide a comprehensive proteomic analysis that supports the positive contribution of a good air quality environment to lung health.

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Section: Discussionmentioning

confidence: 99%

Effects of short-term waterfall forest aerosol air exposure on rat lung proteomics

Zhu¹,

Zhao²,

Zhu³

et al. 2022

Ann Transl Med

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“…Exposure to airborne particulate matter (PM) has been unequivocally linked to various adverse effects on human health, including cardiopulmonary and cerebrovascular diseases, lung cancer, aggravated allergies, and birth defects (Bodor et al 2022;Contini et al 2021;Zhang et al 2022). The severity of the health outcomes depend upon particle size and chemical composition (Kim et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Sensitivity of PM10 oxidative potential to aerosol chemical composition at a Mediterranean urban site: ascorbic acid versus dithiothreitol measurements

Clemente

Gil-Moltó

Yubero

et al. 2023

Air Qual Atmos Health

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The oxidative potential (OP) of PM10 daily samples collected at a traffic site in southeastern Spain during summer and winter was assessed by two acellular assays: the ascorbic acid (AA) and dithiothreitol (DTT) methods. Although PM10 levels were similar during both periods, OP values (expressed in nmol min−1 m−3) showed a defined seasonal trend. The AA activity was higher in summer than in winter, whereas the DTT reactivity exhibited an opposite seasonal pattern. Both assays were sensitive to different PM10 components, as shown by the results of the linear correlation analysis. Moreover, the relationship between OP values and PM10 chemical species was not the same during summer and winter, indicating that particle toxicity is associated with different sources during the warm and cold seasons. When OP values were expressed on a mass basis (nmol min−1 µg−1), lower correlation coefficients with PM10 chemical species were generally obtained compared to volume-normalized activities. These outcomes suggest that only some specific components have a significant intrinsic oxidative potential.

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“…Both acute and chronic diseases caused by long-term PM2.5 exposure include asthma, cough, pneumonia, bronchitis, and high blood pressure (Sánchez-Piñero et al, 2022). In addition to human health, PM2.5 can alter the earth's radiative forcing, change the original chemical cycles, damage the ecosystem, and affect the natural resources such as drinking water, woods, and medical products (Bodor et al, 2022;Linh Thao et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Temporospatial Variation, Chemical Composition, and Source Resolution of PM2.5 in the Southeastern Taiwan Island

Yuan

Ceng

Yen

et al. 2023

Aerosol Air Qual. Res.

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This study investigated the temporospatial variation, chemical composition, and source resolution of fine particles (PM2.5) in the southeastern seas of the Taiwan Island. 24-hr PM2.5 was sampled simultaneously at two remote sites, the Green Island (West Pacific Ocean; WPO) and the Kenting Peninsula (northern Bashi Channel; BC), in four seasons. After sampling, the chemical fingerprints of PM2.5 were characterized and further applied to resolve the potential sources of PM2.5 and their contribution by using a receptor model on the basis of chemical mass balance (CMB), enrichment factor (EF), and backward trajectory simulation. It showed that PM2.5 concentrations in winter (10.8 μg m -3 ) and spring (12.0 μg m -3 ) (i.e., during the period of Asian Northeastern Monsoons; ANMs) were higher than those in summer (4.0 μg m -3 ) and fall (6.6 μg m -3 ). In terms of chemical composition of PM2.5, secondary inorganic aerosols (SIAs = NO3 -, SO4 2-, and NH4 + ) (56.7~67.2%) were the dominant component of water-soluble ions (WSIs) in PM2.5, while crustal elements (Mg, Al, Ca, Fe, and K) (44.0~61.2%) dominated the metallic contents in PM2.5. High EF values (> 10) showed that V, Mn, Ni, Cu, and Zn were potentially contributed from anthropogenic sources. Moreover, organic carbon (OC) (0.6 μg m -3 ) was superior to elemental carbon (EC) (0.3 μg m -3 ) in PM2.5. The OC/EC ratios higher than 2.0 showed the potential chemical formation of secondary organic aerosols (SOAs) in the atmosphere in winter and spring. Trajectory simulation indicated that high PM2.5 concentrations were mostly originated from North and Central China, Japan islands, and Korea Peninsula. Major sources of PM2.5 resolved by CMB receptor modeling were ordered as: sea salts (19.9%) > fugitive dust (19.8%) > industrial boilers (oil-fired) (10.8%) > secondary sulfate (9.8%) > mobile sources (8.0%).

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The human health risk assessment of particulate air pollution (PM2.5 and PM10) in Romania

Cited by 43 publications

References 38 publications

Effects of short-term waterfall forest aerosol air exposure on rat lung proteomics

Effects of short-term waterfall forest aerosol air exposure on rat lung proteomics

Sensitivity of PM10 oxidative potential to aerosol chemical composition at a Mediterranean urban site: ascorbic acid versus dithiothreitol measurements

Temporospatial Variation, Chemical Composition, and Source Resolution of PM2.5 in the Southeastern Taiwan Island

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