The Impact of Adding Digital Breast Tomosynthesis to BI-RADS Categorization of Mammographically Equivocal Breast Lesions

Hassan, Rania; Almalki, Yassir Edrees; Basha, Mohammad Abd Alkhalik; Alduraibi, Sharifa Khalid; Aboualkheir, Mervat; Almushayti, Ziyad; Aldhilan, Asim S.; Aly, Sameh Abdelaziz; Alshamy, Asmaa A.

doi:10.3390/diagnostics13081423

Cited by 4 publications

(2 citation statements)

References 33 publications

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“…While diagnostic imaging is the mainstay in curative and screening protocols, digital breast tomosynthesis (DBT) offers better detection rates by reconstructing a pseudo threedimensional digital mammography thin section series from low-dose X-ray projections from different angles [3]. The advantage of DBT over "classical" 2D mammography is the reduction in the interference between regular breast tissue and possibly obscured tumors [4].…”

Section: Introductionmentioning

confidence: 99%

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The Tomosynthesis Broken Halo Sign: Diagnostic Utility for the Classification of Newly Diagnosed Breast Tumors

Deeg,

Swoboda,

Egle

et al. 2023

Tomography

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Background: Compared to conventional 2D mammography, digital breast tomosynthesis (DBT) offers greater breast lesion detection rates. Ring-like hypodense artifacts surrounding dense lesions are a common byproduct of DBT. This study’s purpose was to assess whether minuscule changes spanning this halo—termed the “broken halo sign”—could improve lesion classification. Methods: This retrospective study was approved by the local ethics review board. After screening 288 consecutive patients, DBT studies of 191 female participants referred for routine mammography with a subsequent histologically verified finding of the breast were assessed. Examined variables included patient age, histological diagnosis, architectural distortion, maximum size, maximum halo depth, conspicuous margins, irregular shape and broken halo sign. Results: While a higher halo strength was indicative of malignancy in general (p = 0.031), the broken halo sign was strongly associated with malignancy (p < 0.0001, odds ratio (OR) 6.33), alongside architectural distortion (p = 0.012, OR 3.49) and a diffuse margin (p = 0.006, OR 5.49). This was especially true for denser breasts (ACR C/D), where the broken halo sign was the only factor predicting malignancy (p = 0.03, 5.22 OR). Conclusion: DBT-associated halo artifacts warrant thorough investigation in newly found breast lesions as they are associated with malignant tumors. The “broken halo sign”—the presence of small lines of variable diameter spanning the peritumoral areas of hypodensity—is a strong indicator of malignancy, especially in dense breasts, where architectural distortion may be obfuscated due to the surrounding tissue.

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Section: Introductionmentioning

confidence: 99%

“…Several studies have shown an increased detection rate for breast cancer by adding DBT to conventional 2D mammography [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

The Tomosynthesis Broken Halo Sign: Diagnostic Utility for the Classification of Newly Diagnosed Breast Tumors

Deeg,

Swoboda,

Egle

et al. 2023

Tomography

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An updated overview of radiomics-based artificial intelligence (AI) methods in breast cancer screening and diagnosis

Elahi,

Nazari

2024

Radiol Phys Technol

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Value of digital breast tomosynthesis in characterization of breast lesions in dense breast

Romeih,

Raafat,

Ahmed

et al. 2024

Egypt J Radiol Nucl Med

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Background Patients with dense breasts have a higher risk factor for developing breast cancer. Digital mammography (DM) exhibits a reduced sensitivity in dense breast tissue as a result of overlapping fibro-glandular tissue. Digital breast tomosynthesis (DBT) solves this problem, so allows better characterization of masses, asymmetries, and parenchymal distortion. It is useful in screening studies for early detection of breast lesions by accurate detection and description of their margins, shape, and extent as well as surrounding structures. Objective We aimed to evaluate the added value of DBT in characterizing of different breast lesions in dense breasts compared to DM. Methods A Prospective Cohort study involved ninety female cases having dense breast parenchyma (ACR C & ACR D) having breast complaint lesions detected by DM or ultrasound or recalled from screening units, during the period from June 2021 to Jan 2023. All patient underwent DM and DBT with correlation with the pathological finding or follow up. Results As regards the characterization of breast mass DBT had higher sensitivity, higher specificity (98%, 87% respectively). However, DM showed less sensitivity, less specificity (58%, 80%,) with (p < 0.0001, p = 0.0005 respectively). Conclusions DBT effectively visualizes overlapping tissue in dense breasts. DBT is important due to its ability to detect breast cancer earlier, characterize lesions accurately, and inspect the margins of masses precisely, along with decreasing recall rates for false-positive results.

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The Impact of Adding Digital Breast Tomosynthesis to BI-RADS Categorization of Mammographically Equivocal Breast Lesions

Cited by 4 publications

References 33 publications

The Tomosynthesis Broken Halo Sign: Diagnostic Utility for the Classification of Newly Diagnosed Breast Tumors

The Tomosynthesis Broken Halo Sign: Diagnostic Utility for the Classification of Newly Diagnosed Breast Tumors

An updated overview of radiomics-based artificial intelligence (AI) methods in breast cancer screening and diagnosis

Value of digital breast tomosynthesis in characterization of breast lesions in dense breast

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