The impact of computerized prescribing on error rate in a department of Oncology/Hematology

Small, Matthew; Barrett, Ann; Price, Gill M

doi:10.1177/1078155208094453

Cited by 32 publications

(42 citation statements)

References 31 publications

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“…In total, seven unique quantitative and two unique qualitative papers met the eligibility criteria for the systematic review ( Figure 1). The research designs described in the quantitative studies included 2-arm trials [17][18][19][20] and pre-post study designs [21][22][23] . The subsection that follows describes the outcomes of the review as they relate to the original research questions.…”

Section: Literature Search Resultsmentioning

confidence: 99%

“…In a much larger study, Small et al 18 also compared manual and computerized complex chemotherapy prescriptions. The error rate was 20.4% in manual orders; in computerized orders, it was 11.8%.…”

Section: The Impact Of St Cpoe On Medication Errorsmentioning

confidence: 99%

“…Four studies 18,19,21,23 demonstrating that cpoe might increase chemotherapy medication errors were identified. Small et al 18 reported that error types differed Beer et al 19 took a different approach, in that they measured the pharmacist intervention rate, which was defined as any problem with a medication order that required physician clarification before the pharmacist could process the order.…”

Section: Generation Of New Errorsmentioning

confidence: 99%

“…Five studies 17,18,[21][22][23] demonstrating that cpoe reduces chemotherapy medication errors in the adult outpatient setting were identified. All reported error reduction for at least some types of errors.…”

Section: The Impact Of St Cpoe On Medication Errorsmentioning

confidence: 99%

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Computerized Prescriber Order Entry in the Outpatient Oncology Setting: From Evidence to Meaningful Use

et al. 2014

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ConclusionsDespite the paucity of oncology-specific research, cpoe should be used in outpatient chemotherapy delivery to reduce chemotherapy-related medication errors. Adoption by clinicians will be enhanced by cpoe processes that complement current practice and workflow processes. KEY WORDSComputerized prescriber order entry, outpatients, systematic review BACKGROUNDChemotherapy is an important type of treatment in the fight against many cancers. The very nature of chemotherapy's toxicity profile also creates potential for harm-and possibly death-if chemotherapy is not ordered, prepared, dispensed, and administered cautiously by members of the health care team.Medication errors can occur anywhere during the medication process from ordering to administration, and errors can compromise patient safety 1,2 . A Canadian study 3 estimated that 7.5% of patients admitted to acute care hospitals in Canada in 2000 experienced at least 1 adverse event. Drug-related adverse events were the second most common type of event, accounting for approximately 24% of all adverse events.Medication errors in oncology can be particularly serious, given the narrow therapeutic window and the high toxicities of antineoplastic drugs 4,5 . In a study conducted by Leape et al. 6 of adverse drug events, 39% of errors occurred in the physician order phase, with drug dosing accounting for 28% of all errors. Specific to chemotherapy, Gandhi et al. 7 revealed that the most common source of error was within the order phase and that, compared with non-chemotherapy medication errors, chemotherapy ABSTRACT Background

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Section: Literature Search Resultsmentioning

confidence: 99%

Section: The Impact Of St Cpoe On Medication Errorsmentioning

confidence: 99%

Section: Generation Of New Errorsmentioning

confidence: 99%

Section: The Impact Of St Cpoe On Medication Errorsmentioning

confidence: 99%

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Computerized Prescriber Order Entry in the Outpatient Oncology Setting: From Evidence to Meaningful Use

et al. 2014

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“…The review that is investigating the effect of CPOE on medication errors showed that it decreased chemotherapy related medication errors in % studies . When manual and computerized chemotherapy prescriptions compared; the error rate was found 20.4% in manual orders and 11.8% in computerized orders and the relative risk (RR) was decreased by 42% (Small et al, 2008).…”

Section: 1699 Medication Errors In Chemotherapy Preparation and Admimentioning

confidence: 99%

Medication Errors in Chemotherapy Preparation and Administration: a Survey Conducted among Oncology Nurses in Turkey

Ulaş

Sılay²,

Akıncı³

et al. 2015

Asian Pacific Journal of Cancer Prevention

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Background: Medication errors in oncology may cause severe clinical problems due to low therapeutic indices and high toxicity of chemotherapeutic agents. We aimed to investigate unintentional medication errors and underlying factors during chemotherapy preparation and administration based on a systematic survey conducted to reflect oncology nurses experience. Materials and Methods: This study was conducted in 18 adult chemotherapy units with volunteer participation of 206 nurses. A survey developed by primary investigators and medication errors (MAEs) defined preventable errors during prescription of medication, ordering, preparation or administration. The survey consisted of 4 parts: demographic features of nurses; workload of chemotherapy units; errors and their estimated monthly number during chemotherapy preparation and administration; and evaluation of the possible factors responsible from ME. The survey was conducted by face to face interview and data analyses were performed with descriptive statistics. Chi-square or Fisher exact tests were used for a comparative analysis of categorical data. Results: Some 83.4% of the 210 nurses reported one or more than one error during chemotherapy preparation and administration. Prescribing or ordering wrong doses by physicians (65.7%) and noncompliance with administration sequences during chemotherapy administration (50.5%) were the most common errors. The most common estimated average monthly error was not following the administration sequence of the chemotherapeutic agents (4.1 times/month, range 1-20). The most important underlying reasons for medication errors were heavy workload (49.7%) and insufficient number of staff (36.5%). Conclusions: Our findings suggest that the probability of medication error is very high during chemotherapy preparation and administration, the most common involving prescribing and ordering errors. Further studies must address the strategies to minimize medication error in chemotherapy receiving patients, determine sufficient protective measures and establishing multistep control mechanisms.

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History and Context of Electronic Prescribing in the US and UK

Goundrey-Smith

2012

Health Informatics

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The impact of computerized prescribing on error rate in a department of Oncology/Hematology

Abstract: The impact of computerized prescribing on adverse drug events requires further evaluation. Prescriber training may be important in further reducing errors. The implementation of all the existing functions of the electronic system should lead to further reduction in errors.

Cited by 32 publications

References 31 publications

Computerized Prescriber Order Entry in the Outpatient Oncology Setting: From Evidence to Meaningful Use

Computerized Prescriber Order Entry in the Outpatient Oncology Setting: From Evidence to Meaningful Use

Medication Errors in Chemotherapy Preparation and Administration: a Survey Conducted among Oncology Nurses in Turkey

History and Context of Electronic Prescribing in the US and UK

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