The Impact of Recent Developments in Electrochemical POC Sensor for Blood Sugar Care

Abstract

Rapid glucose testing is very important in the care of diabetes. Monitoring of blood glucose is the most critical indicator of disease control in diabetic patients. The invention and popularity of electrochemical sensors have made glucose detection fast and inexpensive. The first generation of glucose sensors had limitations in terms of sensitivity and selectivity. In order to overcome these problems, scientists have used a range of new materials to produce new glucose electrochemical sensors with higher sensitivity, selectivity and lower cost. A variety of different electrochemical sensors including enzymatic electrochemical sensors and enzyme-free electrochemical sensors have been extensively investigated. We discussed the development process of electrochemical glucose sensors in this review. We focused on describing the benefits of carbon materials in nanomaterials, specially graphene for sensors. In addition, we discussed the limitations of the sensors and challenges in future research.

Electrospun nanofiber-based glucose sensors for glucose detection

“…The noble metals include gold (Au), silver (Ag), platinum (Pt), and palladium (Pd). The main features of these metals are their unique biological, chemical, and physical specificities, oxidation resistance, and corrosion resistance ( Li et al, 2019 ; Li et al, 2021c ). Nanoscale noble metal materials are flexible, with good biocompatibility and catalytic properties ( Basiri et al, 2018 ; Afzali et al, 2019 ; Amiripour et al, 2021 ; Lakhdari et al, 2021 ).…”

Point-of-care biochemical assays using electrochemical technologies: approaches, applications, and opportunities

“…The immobilization of biomolecules (antibodies or antigens) and the amplification of electrical signals generated by electrochemical reactions are two important factors affecting the performance of immunosensors. A number of materials, including a noble metal nanomaterial and carbon-based materials, have been used to enhance the immobilization of biomolecules and amplify the signals [ 43 ]. However, some couples (e.g., AgNP-biomolecules) can affect the sensitivity and stability of the sensor due to aggregation such that their capacity for amplification is limited.…”

Electrochemical Biosensing of Glucose Based on the Enzymatic Reduction of Glucose

“…Unregulated blood sugar levels in the human body can lead to many life-threatening complications, such as heart disease, stroke, high blood pressure and kidney disease [ 2 , 3 ]. These complications can be delayed and even prevented with careful management of blood glucose (BG) levels [ 4 , 5 , 6 ]. Thus, it is crucial important to monitor BG levels over time, which requires one to have the analytical means to do so.…”