Graphene is a new, advanced material with many possible applications in basic and clinical medicine, electronics and automation. Graphene compounds can be successfully used as an integral part of drug delivery systems, in the construction of transistors, polar processors, touch screens, solar cells and in the production of materials for the manufacture of personal protective equipment, i.e. products and equipment intended to protect the health and life of users. The literature review presented in this paper concerns physical and mechanical properties of composites containing graphene or its structure as well as methods of obtaining polymer, metallic and ceramic composites doped with graphene structures. Data analysis of the potential use of graphene and its composites in personal protective equipment such as monitoring sensors, clothing and security equipment such as ballistic armor, helmets and protective clothing were also reviewed and summarized.