The importance of environmental factors and matrices in the adsorption, desorption, and toxicity of butyltins: a review

Fang, Liping; Xu, Cuihong; Ji, Li; Borggaard, Ole K.; Wang, Dongsheng

doi:10.1007/s11356-017-8449-z

Cited by 42 publications

(20 citation statements)

References 112 publications

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“…In oppervlaktewater worden daarom ook geen relevante (opgeloste) TBTconcentraties verwacht. De mate van sorptie aan sediment is afhankelijk van saliniteit, zuurgraad, temperatuur, concentratie organisch stof, aanwezige mineralen en black carbon (Fang et al, 2017) .…”

Section: Saneringstechniekenunclassified

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Technieken en toepasbaarheid voor de sanering van dioxines en TBT in het Noordzeekanaal : fase 1

Sneekes¹,

Kwadijk²,

Kotterman³

et al. 2017

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De Directie van Wageningen Marine Research is niet aansprakelijk voor gevolgschade, noch voor schade welke voortvloeit uit toepassingen van de resultaten van werkzaamheden of andere gegevens verkregen van Wageningen Marine Research opdrachtgever vrijwaart Wageningen Marine Research van aanspraken van derden in verband met deze toepassing. Dit rapport is vervaardigd op verzoek van de opdrachtgever hierboven aangegeven en is zijn eigendom. Niets uit dit rapport mag weergegeven en/of gepubliceerd worden, gefotokopieerd of op enige andere manier gebruikt worden zonder schriftelijke toestemming van de opdrachtgever.

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Section: Saneringstechniekenunclassified

“…In veel gevallen breekt de vastgelegde stof veel lastiger af dan wanneer deze opgelost zou zijn. Omgevingsfactoren zoals zuurgraad, temperatuur, saliniteit en de aanwezigheid van onder andere aminozuren, mineralen en kool beïnvloeden de mate van adsorptie en desorptie van stoffen zoals TBT (Fang et al, 2017).…”

Section: Adsorptieunclassified

Technieken en toepasbaarheid voor de sanering van dioxines en TBT in het Noordzeekanaal : fase 1

Sneekes¹,

Kwadijk²,

Kotterman³

et al. 2017

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“…OT’s deleterious effects upon wildlife and experimental animals are well documented and include endocrine disruption, immunotoxicity, neurotoxicity, genotoxicity, and metabolic dysfunction including obesity ( 2 , 4 ). Butyltins (BTs) and phenyltins, the major species of OTs, are widely used for agricultural purposes (insecticides, fungicides), in PVC industry, as industrial catalysts, and as additives on boat hull’s paints to avoid encrustations by barnacles, mussels, algae, and other aquatic invertebrates ( 1 – 3 , 5 , 6 ). Therefore, large quantities of OTs have been released into aquatic ecosystems, either directly as wastewater treatment plants or indirectly as hull’s residues, posing serious environmental risks to non-target species ( 5 , 6 ).…”

Section: Introductionmentioning

confidence: 99%

“…Butyltins (BTs) and phenyltins, the major species of OTs, are widely used for agricultural purposes (insecticides, fungicides), in PVC industry, as industrial catalysts, and as additives on boat hull’s paints to avoid encrustations by barnacles, mussels, algae, and other aquatic invertebrates ( 1 – 3 , 5 , 6 ). Therefore, large quantities of OTs have been released into aquatic ecosystems, either directly as wastewater treatment plants or indirectly as hull’s residues, posing serious environmental risks to non-target species ( 5 , 6 ). Even though the use of OTs was banned in 2008, as determined by the International Marine Organization in 2001 ( 7 ), high levels of OTs can still be detected in different matrices such as surface water, clays, quartz, amorphous silica, natural soils, sediments, and organisms ( 5 , 6 , 8 – 10 ).…”

Section: Introductionmentioning

confidence: 99%

Effects of Organotins on Crustaceans: Update and Perspectives

2018

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Organotins (OTs) are considered some of the most toxic chemicals introduced into aquatic environments by anthropogenic activities. They are widely used for agricultural and industrial purposes and as antifouling additives on boat hull’s paints. Even though the use of OTs was banned in 2008, elevated levels of OTs can still be detected in aquatic environments. OTs’ deleterious effects upon wildlife and experimental animals are well documented and include endocrine disruption, immunotoxicity, neurotoxicity, genotoxicity, and metabolic dysfunction. Crustaceans are key members of zooplankton and benthic communities and have vital roles in food chains, so the endocrine-disrupting effects of tributyltin (TBT) on crustaceans can affect other organisms. TBT can disrupt carbohydrate and lipid homeostasis of crustaceans by interacting with retinoid X receptor (RXR) and crustacean hyperglycemic hormone (CHH) signaling. Moreover, it can also interact with other nuclear receptors, disrupting methyl farnesoate and ecdysteroid signaling, thereby altering growth and sexual maturity, respectively. This compound also interferes in cytochrome P450 system disrupting steroid synthesis and reproduction. Crustaceans are also important fisheries worldwide, and its consumption can pose risks to human health. However, some questions remain unanswered. This mini review aims to update information about the effects of OTs on the metabolism, growth, and reproduction of crustaceans; to compare with known effects in mammals; and to point aspects that still needs to be addressed in future studies. Since both macrocrustaceans and microcrustaceans are good models to study the effects of sublethal TBT contamination, novel studies should be developed using multibiomarkers and omics technology.

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“…Butyltin compounds (BTs) are a group of organometallic contaminants that are used as additives of antifouling paints, biocides, and stabilizers . Due to these applications, BTs enter in a diversity of aquatic systems and causing toxic effects in target and non‐target organisms .…”

Section: Introductionmentioning

confidence: 99%

Dibutyltin depressed immune functions via NF‐κB, and JAK/STAT signaling pathways in zebrafish (Danio rerio)

Zhang

Huang

et al. 2017

Environmental Toxicology

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Dibutyltin (DBT) is the degradation products of TBT, which is generally considered higher toxicity than TBT in the immune system. In order to learn more about the mechanisms of immune-toxic of DBT, we exposed zebrafish (Danio rerio) to 0, 1, 10 and 100 ng/L DBT for 8 weeks. At the end of the experiment, we determined the immune parameters and immune-related genes. The results showed that with an increase in TBT dose, lysozyme activities and IgM, C3, C4 content in intestine, skin and spleen were all significantly inhibited by the DBT exposure. Fish exposed to 10 ng/L and 100 ng/L showed significantly lower lysozyme activities and IgM, C3, C4 content than those of the control group. Zebrafish exposed to 10 ng/L and 100 ng/L DBT, the mRNA transcript levels of interleukin-1b (IL-1b), interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-a (TNF-a), interferon g2 (INFg2), nuclear factor-jB p65 (NF-kB p65), inhibitor protein-jBa (IjBa), IjB kinases b (IKKb), Janus family of protein tyrosine kinases (JAKs) and the signal transducers and activators of transcription proteins (STATs) all increased with the DBT levels in the intestine and spleen.Those parameters showed significantly higher values in 10 ng/L and 100 ng/L than those of fish in the control group. However, no significant difference was found in IjB kinases a (IKKa) and IjB kinase g (IKKg) mRNA levels in the intestine and spleen. These data imply that DBT might be via suppression on IKKb/IkBa/NF-kBp65 and JAK/STAT signaling pathways to regulate the immunity of zebrafish.cytokines, dibutyltin (DBT), gene expression, immunity, zebrafish | I N TR ODU C TI ONButyltin compounds (BTs) are a group of organometallic contaminants that are used as additives of antifouling paints, biocides, and stabilizers. 1 Due to these applications, BTs enter in a diversity of aquatic systems and causing toxic effects in target and non-target organisms. [2][3][4] Tributyltin (TBT) is the most investigated of BTs because of its use in antifouling formulations and induction of imposex in gastropod. 5 The use of TBT was totally banned globally in antifouling paints from 2008. 5,6 Even with the prohibition of TBT, the polluted sediments could still be a subject of concern since TBT is relative stable and can release the degradation of dibutyltin (DBT) and monobutyltin (MBT) into water. 5,7 As a major degradation product from TBT, DBT has not been received much attention. However, DBT has been detected in surface water and drinking water at levels of 2 ppb and 53 ng/L. 8 Recently, it is reported that DBT concentrations range from below detection limits (0.38 ng Sn/L) to 23.09 ng Sn/L in the surface water of three Gorges Reservoir Region, China. 9 TBT is generally considered higher toxicity than its degradation product, DBT and MBT, however, with the exception of the immune system, where DBT might have higher toxicity than TBT. 10 It's reported that DBT resulted in a significant decrease at 100 and 200 nM of phagocytotic activity and reduced significantly phagocytic eff...

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The importance of environmental factors and matrices in the adsorption, desorption, and toxicity of butyltins: a review

Cited by 42 publications

References 112 publications

Technieken en toepasbaarheid voor de sanering van dioxines en TBT in het Noordzeekanaal : fase 1

Technieken en toepasbaarheid voor de sanering van dioxines en TBT in het Noordzeekanaal : fase 1

Effects of Organotins on Crustaceans: Update and Perspectives

Dibutyltin depressed immune functions via NF‐κB, and JAK/STAT signaling pathways in zebrafish (Danio rerio)

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