The in vitro intestinal cell model: different co-cultured cells create different applications

Zou, Xingyu; Liu, Yue; Cui, Mengyao; Wan, Qing; Chu, Xiaoqin

doi:10.1080/1061186x.2024.2333877

Journal of Drug Targeting

2024

DOI: 10.1080/1061186x.2024.2333877

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The in vitro intestinal cell model: different co-cultured cells create different applications

Xingyu Zou,

Yue Liu,

Mengyao Cui

et al.

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Application of In Vitro Digestion Models in the Evaluation of Dietary Supplements

Ośko,

Nasierowska,

Grembecka

2024

Foods

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Nowadays, dietary supplements are a permanent part of our diet. Using various simulated in vitro digestive models, the bioavailability of dietary supplement ingredients has also been investigated. In most cases, static models are used instead of dynamic ones. This article focuses on the division of applications of in vitro methods, such as assessing the quality of dietary supplements (in chemical and pharmaceutical form), the impact of diet on the assessment of the bioavailability of product ingredients, the impact of supplement ingredients on the state of intestinal microflora, and the development of new products using various encapsulation methods. The review included publications from 2000 to 2024 showing the use of in vitro methods in dietary supplements containing polysaccharides, proteins, elements, vitamins, and bioactive substances, as well as probiotic and prebiotic products. The impact of components in dietary supplements on the human digestive tract and their degree of bioaccessibility were determined through the use of in vitro methods. The application of in vitro methods has also become an effective tool for designing new forms of dietary supplements in order to increase the availability and durability of labile ingredients in these products.

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Application of In Vitro Digestion Models in the Evaluation of Dietary Supplements

Ośko,

Nasierowska,

Grembecka

2024

Foods

View full text Add to dashboard Cite

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The in vitro intestinal cell model: different co-cultured cells create different applications

Cited by 1 publication

References 153 publications

Application of In Vitro Digestion Models in the Evaluation of Dietary Supplements

Application of In Vitro Digestion Models in the Evaluation of Dietary Supplements

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