The Indian Herbal Drugs Scenario in Global Perspectives

Ramawat, K. G.; Goyal, Shaily

doi:10.1007/978-3-540-74603-4_18

Cited by 60 publications

(40 citation statements)

References 65 publications

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“…Compounds that are identified by activity-guided fractionation must be tested in appropriate animal models to confirm in vivo activity. Ideally, the composition of the total botanical extract must be standardized and free of any potential hazards, and plants should be grown specifically for the production of botanical extracts under controlled conditions and originate from a characterized and uniform genetic source with a taxonomic record of the genus, species, and cultivar or other additional identifiers (Chavez et al, 2006;Jagtenberg et al, 2003;Mahady, 2001;Balunas et al, 2005;Ramawat et al, 2008;Thirumalai et al, 2011;Tilburt et al, 2008;Yadav et al, 2008). Because the environment can significantly affect phytochemical profiles and the efficacy of the botanical end product, botanical extracts can vary from year to year and may be significantly affected by temperature, drought, or flood as well as by geographic location.…”

Section: Threats and Challengesmentioning

confidence: 99%

“…The correct identification of medicinal plant is one of the major problems in both the system. This should be corrected with the modern tools and techniques (Barnes, 2003;Parray et al, 2012;Ramawat et al, 2008;World Health Organization, 1998). Further, to explore them on the basis of new scientific basis, we need an interaction with multidisciplinary team work including ethno-botanists, pharmacologists, physicians and phytochemists for the fruitful outcome of medicinal plants research.…”

Section: Introductionmentioning

confidence: 99%

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Herbal pathies (Unani, Ayurveda) need to review their way of research

Parray¹,

Parray²,

Zohaib³

et al. 2017

TANG [HUMANITAS MEDICINE]

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World health organization has recently published a strategic plan for the development and promotion of traditional system of medicine. Herbal pathies especially Unani and Ayurvedic systems of medicines have great scope in this aspect. But, there are several problems with these pathies in the current era, as the way of research and identification is still on classical system. The correct identification of medicinal plant is one of the major problems in both the system. This should be corrected with the modern tools and techniques. The various types of data including recent discoveries, economical growth, ethnobotanical literature and extremely rapid increase in herbal journals and books have emerged great scope for these pathies. At the same time several challenges and threats are present including herb-drug interaction, false reports, toxicity studies etc. In this review paper, opportunities, threats, and researches to be focused will be discussed.

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Section: Threats and Challengesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Herbal pathies (Unani, Ayurveda) need to review their way of research

Parray¹,

Parray²,

Zohaib³

et al. 2017

TANG [HUMANITAS MEDICINE]

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“…Plants are a potential source of a large number of valuable metabolic products (Ramawat and Goyal 2008;Ramawat et al 2009). Biotic and abiotic elicitors are frequently used to stimulate the biosynthetic activity to optimize the secondary metabolites accumulation in plant cell cultures (Zhao et al 2005), which is finding commercial applications (Savitha et al 2006).…”

Section: Introductionmentioning

confidence: 99%

Marked effect of Cuscuta on puerarin accumulation in cell cultures of Pueraria tuberosa grown in shake flasks and a bioreactor

Goyal

Sharma

Ramawat

2011

Plant Biotechnol Rep

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Isoflavonoid production in cell cultures of Pueraria tuberosa as influenced by an angiospermic parasite, Cuscuta reflexa, was studied. During the time course, maximum isoflavonoid content was recorded when Cuscuta elicitor was added on day 15 of culture. Among various concentrations of elicitor tried, 1 g l -1 of Cuscuta elicitor was found to be the most effective. The optimized elicitation conditions were used in vessels of varying capacity where maximum yield of *91 mg l -1 of isoflavonoid was recorded in a 2-l bioreactor which was about 19% higher than the control cultures. In this case, puerarin content increased up to 11 mg l -1 which was 580% higher that the value recorded in the control cultures. In the bioreactor, 8 days of elicitation was optimal for the high accumulation of isoflavonoid, giving productivity of *4 mg l -1 day -1 . The study showed persistent high isoflavonoid yield even during scale-up. Use of a preparation of Cuscuta reflexa as an elicitor is reported for the first time. The increase in isoflavonoid content was elicitor dose-dependent and can be explored to trigger high yields of isoflavonoid/secondary metabolites in production.

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“…Traditional medicine has maintained its popularity in all regions of the developing world, and its use is rapidly spreading in industrialized countries (Ramawat and Goyal, 2008). Knowledge of plants and their healing properties have been closely linked from the time of human beings' earliest social and cultural groupings.…”

Section: Introductionmentioning

confidence: 99%

Study of indigenous/traditional medicinal plant knowledge-An endeavour towards new drug discovery.

Lone¹,

Bhardwaj²,

Bahar³

2015

Afr. J. Trad. Compl. Alt. Med.

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The documentation and phytochemical screening of medicinal plants has been an important way over the years for the discovery of new drugs and pharmaceutical products. Bandipora, one of the northern districts of Kashmir, India, is rich in ethnic and biological diversity. Owing to increasing demand and subsequent pressure on medicinal plants, it is highly imperative to document their traditional uses, understand their distribution and diversity, and highlight their availability in their natural habitats. To this end, the present study was carried out to elicit a firsthand wealth of information on the traditional medicinal uses of plants practiced by the local populace of this remote district. Material and Methods: Frequent field trips and plant collections were made between March 2011 to October 2012 and the methods used to gather ethnomedicinal data included semi-structured interviews, focus group discussions and walk-in-the-woods with local knowledgeable elders, traditional practitioners (Bhoeris) and tribals (Gujjars and Bakkerwals). The collected data was analyzed with three quantitative tools viz. the informant consensus factor (F ic ), fidelity level (FL) and use value (UV). Results: A total of 131 plant species belonging to 120 genera and 59 different families were found to be used as remedies for curing various human and livestock ailments. Out of 131 species, angiosperms comprised the highest number (124 species) followed by pteridophytes (4 species) and gymnosperms (3 species). Two dominant families were Asteraceae (16 species) and Lamiaceae (9 species). The highest informant's consensus factor (F ic ) value was 0.95 for insect stings, followed by dermatological, hair ailments, anticancer/tumor (0.90 each), which indicated best agreement among informant knowledge on medicinal plant used to treat ailments in these categories while the lowest F ic value of liver disorders and fever (0.63 each) indicated less agreement among informant knowledge on medicinal plant used to treat ailments in these categories. The 100% FL was expressed by 6 plant species for dermatological disorders followed by 3, 1, 1, 1 and 1 for mouth ailments, cardiovascular, joint ailments, gastrointestinal and insect stings category respectively. Use value was high for Artemisia absinthium (0.70), Cannabis sativa and Saussurea costus (0.47 each), Calendula officinalis (0.45) and Taraxacum officinale (0.39). The lowest use value was calculated for Ranunculus arvensis (0.01), with only three people reported the utility. Conclusion: Since drug discovery from medicinal plants continues to provide new and important leads against various pharmacological targets, an effort to collect medicinal plants and their associated traditional knowledge could serve an important tool for the discovery new potent compounds because if the documented plants are subjected to thorough phytochemical and pharmacological investigations, new potent leads against various pharmacological targets could definitely be discovered as there is no doubt that botanic gems are...

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The Indian Herbal Drugs Scenario in Global Perspectives

Cited by 60 publications

References 65 publications

Herbal pathies (Unani, Ayurveda) need to review their way of research

Herbal pathies (Unani, Ayurveda) need to review their way of research

Marked effect of Cuscuta on puerarin accumulation in cell cultures of Pueraria tuberosa grown in shake flasks and a bioreactor

Study of indigenous/traditional medicinal plant knowledge-An endeavour towards new drug discovery.

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