The influence of polycyclic aromatic hydrocarbons on lung function in a representative sample of the Canadian population

Abstract

We investigated the associations between exposure to polycyclic aromatic hydrocarbons (PAHs) and selected respiratory physiologic measures in cycles 2 and 3 of the Canadian Health Measures Survey, a nationally representative population sample. Using generalized linear mixed models, we tested the association between selected PAH metabolites and 1-second forced expiratory volume (FEV), forced vital capacity (FVC), and the ratio between the two (FEV/FVC) in 3531 people from 6 to 79 years of age. An interquartile change in urinary PAH metabolite was associated with significant decrements in FEV and FVC for eight PAHs, 2-hydroxynapthalene, 1-, and 2-hydroxyphenanthrene, 2-, 3-, and 9-hydroxyfluorene and 3- and 4-hydroxyphenanthrene. Exposure to PAH may negatively affect lung function in the Canadian population.

In vitroremoval of polycyclic aromatic hydrocarbons by lactic acid bacteria

“…; Bansal and Kim ; Cakmak et al . ). Therefore, various foodstuff such as meat products, oil and fat, cereal, smoked food products, seafood, tea and coffee can be contaminated by PAHs during food processing, cooking and environmental pollution (Farhadian et al .…”

“…Since PAHs are ubiquitous environmental pollutants, they can contaminate air, soil and ground water and finally enter into the food chain. Furthermore, generation of PAHs during various food preparation processes such as smoking, roasting, frying, barbecuing, baking and drying can contaminate food (Purcaro et al 2013;Bansal and Kim 2015;Cakmak et al 2017). Therefore, various foodstuff such as meat products, oil and fat, cereal, smoked food products, seafood, tea and coffee can be contaminated by PAHs during food processing, cooking and environmental pollution (Farhadian et al 2010;Dost and Deli 2012).…”

Exposure to polycyclic aromatic hydrocarbons, vitamin D, and lung function in children with asthma

“…In this analysis, we included children (6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) The best FEV 1 , FVC, and the FEV 1 /FVC ratio were selected for analysis. Percent (%) predicted and z-score of FEV 1 , FVC, and FEV 1 /FVC were calculated using Global Lung Initiative equations that account for age, sex, race/ethnicity, and height.…”

“…[8][9][10] . Although several studies have also linked PAH exposure to reduced lung function measures (forced expiratory volume in 1 s (FEV 1 ) and forced vital capacity (FVC)) among children and adults in the general population, [11][12][13] little is known about PAH exposure and lung function or eosinophilic airway inflammation in children with asthma, who may be particularly susceptible to the detrimental effects of air pollutants. In the only study examining PAH exposure and lung function among children with and without asthma, exposure to the sum of PAH with 4, 5, or 6 rings for 3 months to 1 year was significantly associated with reduced post-bronchodilator FEV 1 among 162 children without asthma, but not among 135 children with asthma.…”

The Public Value of Reducing the Incidence of Oil Spill Accidents in Korean Rivers

“…Oil can contain more than one hundred contaminants, all of which are hazardous and toxic substances [1]. Therefore, if humans and animals are exposed to these substances, they may cause various diseases, such as cancer, genotoxicity, fetal growth defects, cardiovascular disease, DNA adducts in fish, bioaccumulation, and so on [1][2][3][4][5].…”