Effects of preheating times (4, 8, and 12 min), preheating temperatures (75-210 °C, with 15 °C interval), and their interactions on structures and density profiles of sandwich compressed poplar wood (Populus × euramericana cv. 'Neva') were studied to achieve better control of the position(s) of compressed layer(s), with the aim of better utilization of the low-density wood resources. Our findings revealed that, as a result of preheating temperature elevation or preheating time extension, compressed layers move gradually from wood surfaces to wood interior center, forming three types of sandwich compressed wood, namely, surface compressed wood, internal compressed wood, and central compressed wood. The characteristics of wood cell deformation in the sandwich compressed wood match well with the density distribution, and no obvious cell-wall cracks were observed. Effects of preheating temperature, preheating time, and preheating temperature-time interaction on the density of the compressed layer(s) are statistically insignificant. But their effects on the position and thickness of the compressed layer(s) in the sandwich compressed wood were statistically highly significant (p < 0.001), and the preheating temperature and compressed layer(s) positions were significantly related to the functions and fitted the polynomial of the fourth order. which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.