This study explores Indian library and information science (LIS) professionals’ perspectives on the integration of artificial intelligence (AI) in academic libraries in India. It aims to evaluate their comprehension of AI, determine their perspectives, investigate AI utilization, assess advantages, identify influencing factors, and examine attitudes towards AI adoption. A quantitative research approach was employed, utilizing a structured questionnaire designed based on study objectives and reviewed by subject matter experts. Purposive sampling targeted individuals with relevant LIS knowledge. Data were collected through Google Forms from 259 respondents and analysed using descriptive and inferential statistics. Respondents generally exhibited positive perceptions towards AI integration in libraries. High mean scores were observed for statements such as “AI can bridge librarian performance gaps” and “AI does not make library staff lazy.” Librarians expressed willingness to learn about AI, interest in its ethical implications, and confidence in its potential to improve library services. The study highlights a cautious optimism towards AI adoption in Indian academic libraries, with recognition of its potential benefits tempered by concerns about employment and resource allocation. Librarians demonstrate proactive attitudes towards engaging with AI technology and understanding its implications for library services, indicating a readiness to embrace AI within the profession.