The interaction between antioxidant status and cervical cancer: A case control study

Abstract

Levels of antioxidants significantly differed between the patients with cervical cancer and the controls, and no change in antioxidant levels was observed after treatment. Moreover, further studies evaluating the predictive value of glutathione levels on treatment response are warranted.

A STUDY OF SERUM MDA & TAC IN PATIENTS OF CERVICAL CANCER

“…Similar results were found by Senem et al who found that antioxidant status is altered in patients with cervical cancer compared to healthy controls 13 (Senem Demirici, et al, 2011). According to Chung et al, the cervical intraepithelial neoplasia was also associated with lower blood antioxidant capacity levels 14 (Chung HW, et al, 2004).…”

“…Same results of elevated MDA levels were found in patients with cervical cancer compared to a control group by Senem Demirici et al, who stated oxidative damage leads to the formation of products like MDA and DNA damage may lead to mutagenesis, carcinogenesis and cell death 13 (Senem Demirici et al, 2011).…”

Pre and post radiotherapy serum oxidant/antioxidant status in breast cancer patients: Impact of age, BMI and clinical stage of the disease

“…37 In another survey by Demirci et al on antioxidant status in 35 cervical cancer patients, the authors did not find significant differences between the levels of SOD, MDA and GPx status pre-RT and post-RT. 38 According to our knowledge, the reports regarding to the impact of age on the oxidant/antioxidant variables are limited. As previously mentioned in two age groups of patients, RT led to a significant decrease in some variables (GPx, SOD and TAS) and a non-significant increase in MDA and CAT levels.…”

The significance of reduced glutathione and glutathione S-transferase during chemoradiotherapy of locally advanced cervical cancer

“…Demirici et al [16] examined GSH, GSH-Px and SOD concentrations and the malondialdehyde (MDA) level before and after (chemo)radiotherapy in 35 patients, and compared the results to data from a control group of 35 healthy women. Antioxidant levels differed significantly between patients and healthy women.…”