The Jessner's + TCA Peel: A Medium‐Depth Chemical Peel

Abstract

Abstract. The Jessner's + TCA peel, a method of chemexfoliation, is a combination of two acidic compounds. It has been found to be an effective peeling procedure that produces a medium‐depth peel for photoaging skin, actinic keratoses, and rhytides.

Pilot Ultrastructural Evaluation of Human Preauricular Skin Before and After High-Energy Pulsed Carbon Dioxide Laser Treatment

“…[26][27][28][29][30][31][32][33][34][35][36][37][38]50 The increased number and organization of the tonofibrils in epidermal keratinocytes that we have seen at 30 and 90 days after laser treatment appears therefore to be significant, as these findings correlate with the normalization of keratinocyte differentiation from the basal layer to the stratum corneum seen histologically after laser resurfacing. Additionally, the loss of intracellular and intercellular epidermal vacuolization and the presence of folded and tightly apposed intercellular spaces of adjacent keratinocytes studded at intervals with innumerable desmosomes 30 and 90 days after treatment appear to be significant, as these findings are characteristically seen in normal squamous epithelium.…”

“…39,46,47 The clinically evident tightening of sagging skin after laser surfacing may be in part due to the formation of new collagen, the decrease in the amount of amorphous debris in the papillary dermis, and the increased activity and number of fibroblasts that have been documented histologically and ultrastructurally after laser and other resurfacing procedures. [26][27][28][29][30][31][32][33][34][35][36]38,50 Nelson et al 34 have in fact found that collagen's striation periodicity is reduced after medium-depth chemical peels, resulting in a more compact architecture, and that the diameter of individual fibrils is more variable, consistent with recent production of collagen by activated fibroblasts. Precise quantitative studies will be required to substantiate whether compression of the collagen bundles occurs immediately after laser resurfacing and whether the striation periodicity of the collagen is immediately changed after treatment.…”

“…20,24,25 Dramatic clinical and histologic improvement in photoaged skin may also be produced with medium-depth and deep chemical peeling agents and dermabrasion. [26][27][28][29][30][31][32][33][34][35][36][37] When properly performed, both procedures result in architectural and cytologic normalization of the epidermis, as well as an expanded papillary and reticular dermis composed of dense, parallel arrays of collagen bundles, otherwise known as the dermal repair zone. Nelson et al 34 were the first to document the ultra-OBSERVATION tural changes produced by medium-depth chemical peels on photodamaged facial skin.…”

Chemical Peel

“…Die Wir kung mit tel tiefer Peels durch die Kom bi na ti on zwei er we ni ger tief ein dringen der Sub stan zen wur de in den 80er-Jah ren von Bro dy so wie von Mon heit be schrieben [8,30].…”

Chemexfoliation and Superficial Skin Resurfacing

“…Jessner's solution was formulated to lower the concentration and toxicity of any one agent and to enhance the keratolytic effects. Jessner's solution has intense keratolytic activity, initially causing loss of corneocyte cohesion within the stratum corneum and subsequently creating intercellular and intracellular edema within the upper epidermis if application is continued [37].…”