The Level of Serum MFG-E8 in Liver Cancer and Its Metastasis in Liver Cancer

Abstract

Objective: to detect the level of MFG-E8 in serum of patients with liver cancer and its role in liver cancer. Methods: ELISA was used to detect the level of MFG-E8 in serum. Molecular cloning was used to construct MFG-E8 eukaryotic expression vector. MTT assay and Migration assay were used to detect the proliferation and metastasis of HCC. Results: the level of MFG-E8 in patients' serum with liver cancer was significantly increased, which has a good value in the diagnosis of liver cancer, and is positively correlated with the level of AFP. Overexpression of MFG-E8 can promote the metastasis of liver cancer. Conclusion: the level of serum MFG-E8 in patients with liver cancer is high, and it can promote the metastasis of liver cancer.