2018
DOI: 10.4172/1747-0862.1000356
|View full text |Cite
|
Sign up to set email alerts
|

The Long Non-Coding RNA XIST: A New Cornerstone in Carcinogenesis

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
3
0

Year Published

2020
2020
2024
2024

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(3 citation statements)
references
References 0 publications
0
3
0
Order By: Relevance
“…lncRNAs represent ideal candidates as novel BC immune biomarkers due to their stability and their massive involvement in BC carcinogenesis (24,25,(36)(37)(38). A mounting body of evidence highlighted different contributing roles of the lncRNA XIST either as an oncogene or as a tumor suppressor gene in diverse cancers (39)(40)(41)(42)(43). Nonetheless, limited evidence displayed lncRNA XIST involvement as a tumor suppressor lncRNA in BC (28,29) in addition to the absence of concerns regarding lncRNA TSIX, the negative regulator of lncRNA XIST in BC.…”
Section: Discussionmentioning
confidence: 99%
“…lncRNAs represent ideal candidates as novel BC immune biomarkers due to their stability and their massive involvement in BC carcinogenesis (24,25,(36)(37)(38). A mounting body of evidence highlighted different contributing roles of the lncRNA XIST either as an oncogene or as a tumor suppressor gene in diverse cancers (39)(40)(41)(42)(43). Nonetheless, limited evidence displayed lncRNA XIST involvement as a tumor suppressor lncRNA in BC (28,29) in addition to the absence of concerns regarding lncRNA TSIX, the negative regulator of lncRNA XIST in BC.…”
Section: Discussionmentioning
confidence: 99%
“…274). LncRNA XIST has been extensively studied by our research group (Refs 275, 276). LncRNA XIST acted as a tumour suppressor where it was downregulated in BC tissues (Ref.…”
Section: Non-coding Rna and Inflammasomes In Breast Cancermentioning
confidence: 99%
“…LncRNA XIST acted as a tumour suppressor where it was downregulated in BC tissues (Ref. 275) and was able to suppress PD-L1 expression in MDA-MB231 cells (Refs 275, 276). In addition, PD-L1-overexpressing BC patients as well as TNBC cell lines showed an inverse correlation with low levels of XIST, where XIST was described as non-invasive cancer immune biomarker for anti-PD-L1 personalised therapy (Ref.…”
Section: Non-coding Rna and Inflammasomes In Breast Cancermentioning
confidence: 99%