The macular edema

Malla, Om Krishna

doi:10.3126/nepjoph.v3i2.5259

Cited by 1 publication

(2 citation statements)

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“…The most common type of glaucoma diagnosed in our study population was angle closure glaucoma. The incidence of angle closure glaucoma in Caucasians has been reported as 0.1-0.2 % and in East Table 6 Post-operative bleb score Malla P et al Nep J Oph 2010;2(3):16-25 Use of 5-FU in trabeculectomy Table 7 Post-operative complications in various groups Asians as 0.3-3.2 % (Yanoff M, 2004). Following closely to this, primary open angle glaucoma patients were 30 % in group A, 50 % in group B and 40 % in group C. The prevalence of POAG varies according to the study population.…”

Section: Discussionmentioning

confidence: 99%

“…In group A, 5 patients had improved in Snellen's acuity by 2 or more lines and 5 had no change. In group B, 2 Table 2 Pre-operative visual acuity in logMAR Table 4 Pre-operative and post-operative intraocular pressure and reduction percentage Table 3 Post-operative intra-ocular pressure Table 5 Median post-operative anterior chamber depth Malla P et al Nep J Oph 2010;2(3):16-25 Use of 5-FU in trabeculectomy patients had improvement and 8 had no change, whereas in group C, 4 patients had improvement and 6 had no change.…”

Section: Post-operative Evaluationmentioning

confidence: 99%

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Effectiveness of intra-operative and post-operative use of 5-Fluorouracil in trabeculectomy – a randomized clinical trial

Malla

Das

1970

Nep J Oph

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Introduction: The success rate of trabeculectomy is limited by postoperative scarring. Objective: To evaluate the effectiveness of intra-operative and post-operative use of 5- Fluorouracil (5-FU) in trabeculectomy Materials and methods: Thirty consecutive eyes undergoing trabeculectomy were randomized systematically into 3 groups of ten patients each. Group A served as a control; in Group B intraoperative 5-FU was used, whereas Group C received post-operative sub-conjunctival 5-FU. The variables studied were pre- and post-operative intraocular pressure, post-operative bleb characteristics and complications. Statistics: Data were evaluated using the SPSS ver 10.0 program. ANOVA, paired t test and chi2 tests were performed. Results: The means of age in years of patients in group A, B and C were 49 ± 9.23, 56.50 ± 8.39 and 52.10 ± 8.96 respectively (p = 0.222). The means of pre-operative IOP in groups A, B and C were 37.80 ±10 mmHg, 42.00 ± 11.22 mmHg and 29.40 ± 12.82 mmHg respectively. The medians of pre-operative anterior chamber depth (ACD) in groups B and C were 3 and 2 in group A according to van Herrick's grading. The mean values of final IOP were 11.90± 3.50, 11.70 ± 4.24, 11.00 ± 2.83 mmHg (p=0.841). The median post-operative anterior chamber depth in all the groups was similar compared to the pre-operative anterior chamber depth (p= 0.510). The final bleb scores in all the groups were similar (p=0.873). Conclusion: The intra-operative and post-operative use of 5-FU in trabeculectomy is almost equally effective in terms of IOP control and bleb characteristics. Keywords: trabeculectomy; 5-Fluorouracil; glaucoma DOI: 10.3126/nepjoph.v2i1.3699 Nep J Oph 2010;2(1):16-25

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Section: Discussionmentioning

confidence: 99%

Section: Post-operative Evaluationmentioning

confidence: 99%