The Medipix3 Prototype, a Pixel Readout Chip Working in Single Photon Counting Mode with Improved Spectrometric Performance

Ballabriga,; Campbell, D. M.; Heijne,; Llopart,; Tlustos,

doi:10.1109/nssmic.2006.353767

Cited by 89 publications

(96 citation statements)

References 5 publications

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“…The new generation of imaging detectors Medipix3 contains electronics that treats the charge sharing effect within the pixel readout by summing the charge deposited in neighbouring pixels [20]. Therefore, the spectral response of the Medipix3 should be signi¿cantly improved.…”

Section: Discussionmentioning

confidence: 99%

X-ray fluorescence imaging with the Medipix2 single-photon counting detector

Uher

Harvey

Jakůbek

2010

IEEE Nuclear Science Symposuim &Amp; Medical Imaging Conference

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Abstract-Material-resolved X-ray imaging or colour X-ray imaging is of a great interest for many applications ranging from physics, industry to medicine and biology. X-ray Àuorescence offers a method for producing such images if the energies and positions of origin of the Àuorescent photons can be adequately resolved.This paper describes application of the Medipix2 single photon counting imaging detector (256 256 pixels each of 55 55 m size) for this purpose.The basics of the method are explained including details of the energy calibration of all 65 k individual pixels. The effect of charge sharing is discussed and a method for its characterisation based on numerical calculation presented. The charge sharing calculation is then used to generate the Medipix2 detector response matrix, which is subsequently used for analysis of measured spectra in detector pixels.

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Section: Discussionmentioning

confidence: 99%

X-ray fluorescence imaging with the Medipix2 single-photon counting detector

Uher

Harvey

Jakůbek

2010

IEEE Nuclear Science Symposuim &Amp; Medical Imaging Conference

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“…Additionally, neighbouring pixels will communicate with one another on an event by event basis, to reduce the effects of charge sharing. These advances will create true, spectroscopic images with improved energy and spatial resolution 18 . With a move to 3-D spectroscopic reconstructions, the mass attenuation curve of each particular structure within the body could be individually identified, decreasing artefacts and improving diagnostic power 4 .…”

Section: Discussionmentioning

confidence: 99%

“…CERN (Conseil Européen pour la Recherche Nucléaire) designed and developed the Medipix2 detector 18 . The photon counting pixel detector uses a semiconductor sensor layer to directly convert x-ray photons into electron-hole pairs.…”

Section: Dual-energy Medipix2 Imagingmentioning

confidence: 99%

Spectroscopic biomedical imaging with the Medipix2 detector

Melzer

Cook

Butler

et al. 2008

Australas. Phys. Eng. Sci. Med.

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This study confirms that the Medipix2 x-ray detector enables spectroscopic bio-medical plain radiography. We show that the detector has the potential to provide new, useful information beyond the limited spectroscopic information of modern dual-energy computed tomography (CT) scanners. Full spectroscopic 3D-imaging is likely to be the next major technological advance in computed tomography, moving the modality towards molecular imaging applications. This paper focuses on the enabling technology which allows spectroscopic data collection and why this information is useful. In this preliminary study we acquired the first spectroscopic images of human tissue and other biological samples obtained using the Medipix2 detector. The images presented here include the clear resolution of the 1.4mm long distal phalanx of a 20 week old miscarried foetus, showing clear energy-dependent variations. The opportunities for further research using the forthcoming Medipix3 detector are discussed and a prototype spectroscopic CT scanner (MARS, Medipix All Resolution System) is briefly described.

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“…When, at the end of the shutter time, the chip is readout, each pixels yields a digital value telling how many quanta with energy comprised in the pre-set window were detected during the exposure. In the Medipix3 chip [4], each pixel hosts two simultaneous counters, each connected to one of PoS(TIPP2014)246 the discriminators. Pixels can be logically grouped in 2 × 2 clusters that behave as 110 µm pitch super-pixels with 8 energy thresholds.…”

Section: The Medipix Chipmentioning

confidence: 99%

“…This means that spectral information can be added to conventional X-ray images. Such detectors can be constructed by coupling a semiconductor pixel sensor to an energy resolving readout chip, like those of the Medipix and Timepix family [3,4,5]. In this case one speaks of hybrid semiconductor pixel detectors.…”

Section: Introductionmentioning

confidence: 99%

Prospects for spectral CT with Medipix detectors

Schioppa¹,

Visser²,

Koffeman³

2015

Proceedings of Technology and Instrumentation in Particle Physics 2014 — PoS(TIPP2014)

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In the development of X-ray Computed Tomography (CT) in medical imaging, one is working to implement spectral information. While keeping the dose level the same, or even lower, than in conventional systems, spectral CT offers the possibility to measure energy dependent features of different tissues that will allow the extraction of additional information about the patient, eventually leading to real color CT. Spectral CT can be achieved through the application of energy sensitive pixel detectors, such as Medipix-based semiconductor devices and by the implementation of reconstruction algorithms where the energy information is taken into account. In this paper, we present the latest results of our work on spectral CT with Medipix detectors and specifically on detector characterization and the development of algorithms that include energy information. Technology and Instrumentation in PoS(TIPP2014)246Prospects for spectral CT with Medipix detectors Enrico Jr. Schioppa (a) Bare readout pixel matrix.(b) ASIC bump-bonded to a silicon sensor.

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The Medipix3 Prototype, a Pixel Readout Chip Working in Single Photon Counting Mode with Improved Spectrometric Performance

Cited by 89 publications

References 5 publications

X-ray fluorescence imaging with the Medipix2 single-photon counting detector

X-ray fluorescence imaging with the Medipix2 single-photon counting detector

Spectroscopic biomedical imaging with the Medipix2 detector

Prospects for spectral CT with Medipix detectors

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