The aim of this study was to identify the mediating effect of employee engagement in the relationship between its antecedents and consequences (i.e. job satisfaction). A random sample comprising 250 subjects from academic institutions in Jordan was used to collect the required data. Of the250 questionnaires distributed, 238 were returned and considered valid for analysis. The findings showed that all mediation conditions were verified. That is, employee engagement mediated the relationship between employee communication, clear career growth opportunities, employees' pride in their organization, managers' trust and integrity, rewards and recognition, feedback and mentoring, work motivation, psychological empowerment, internal corporate social responsibility (CSR) practices, organizational and supervision support and organizational justice, as well as organizational culture and job satisfaction. Hence, managers should take these antecedents into account to keep their employees engaged and satisfied.