The mouse and the rat in surgical research. The anesthetic approach

Abstract

The mouse and the rat are currently overwhelmingly preferred as laboratory animals. Surgical research on animals requires anesthesia and analgesia to obtain adequate immobility and to reduce stress and pain. Small rodent anesthesia is challenging for several reasons including the animals’ size, metabolic rate, high risk of hypothermia and difficulty in monitoring. The purpose of this study is to create an overview of the information in the anesthetic practices for small rodents, in particular mice and rats.

Experimental Animal Models for Studying Intestinal Obstruction

“…Inhalant anesthetics can be used by anesthetic chamber or face mask and maintained using a face mask (in smaller animals especially) or an endotracheal tube. Although inhaled anesthesia is considered safer than injectable, its use in literature is limited to larger animals due to lack of equipment or expertise of the researchers [47,50,52].…”