2004
DOI: 10.1001/archinte.164.19.2141
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The National Cholesterol Education Program Diet vs a Diet Lower in Carbohydrates and Higher in Protein and Monounsaturated Fat

Abstract: Compared with the NCEP diet, the MLC diet, which is lower in total carbohydrates but higher in complex carbohydrates, protein, and monounsaturated fat, caused significantly greater weight loss over 12 weeks. There were no significant differences between the groups in blood lipid levels, but favorable changes were observed within the MLC diet group.

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Cited by 70 publications
(53 citation statements)
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“…7,29,30 However, there is some evidence to suggest that diets relatively low in total carbohydrate may confer benefits in terms of cardiovascular risk determinants in individuals with metabolic syndrome. 4,[31][32][33] The results of our study confirm that 2 of the most widely promoted dietary prescriptions for weight loss are equally effective options for individuals attempting to maintain their weight after weight loss. It is also reassuring that further weight loss represents a reduction in body fat and not lean body mass, that central adiposity is reduced, and that several other cardiovascular risk determinants (blood pressure, fasting glucose, triglycerides and insulin) are improved.…”
Section: Discussionsupporting
confidence: 72%
“…7,29,30 However, there is some evidence to suggest that diets relatively low in total carbohydrate may confer benefits in terms of cardiovascular risk determinants in individuals with metabolic syndrome. 4,[31][32][33] The results of our study confirm that 2 of the most widely promoted dietary prescriptions for weight loss are equally effective options for individuals attempting to maintain their weight after weight loss. It is also reassuring that further weight loss represents a reduction in body fat and not lean body mass, that central adiposity is reduced, and that several other cardiovascular risk determinants (blood pressure, fasting glucose, triglycerides and insulin) are improved.…”
Section: Discussionsupporting
confidence: 72%
“…30 Also, favorable but not significant increase in HDL-C concentration was observed with modified lower carbohydrate diet. 31 Dietary habit was not quantitatively measured, in this sense, inaccuracy was unavoidable, and thus may have failed to detect a real association between fatty diet and HDL-C level. As shown in the multiple regression analysis only 17.9% of the variation in HDL-C concentration was related to lifestyle factors, sex, and age.…”
Section: Discussionmentioning
confidence: 99%
“…Women experience a greater increase in HDL-C levels than men after stroke, possibly due to endogenous estrogens regulating apoA-I [12]. Lifestyle modification including diet, smoking cessation, alcohol consumption, and exercise have shown conflicting results in terms of the percent increase in HDL-C after intervention; changes in these parameters likely have a modest effect on HDL-C levels in the first few weeks following stroke presentation [16][17][18]. The increase in HDL-C levels we observed exceeds the anticipated increase in HDL-C which may be attributed to statin use or lifestyle modification during this period.…”
Section: Discussionmentioning
confidence: 99%