The need to be alert to complications of peri‐lead cerebral edema caused by deep brain stimulation implantation: A systematic literature review and meta‐analysis study

Abstract

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Which one is the superior target? A comparison and pooled analysis between posterior subthalamic area and ventral intermediate nucleus deep brain stimulation for essential tremor

“…Furthermore, one-arm metaanalysis is also regarded as a reliable method to provide level IIIa evidence. 20,21,79,80 Second, because most of the follow-up times in PSA-DBS were in 12-24 months, and our outcomes mainly reflected medium-longterm results, more studies are needed to better compare short-term and long-term efficacies.…”

“…However, more ET patient samples were included in this way, which improved the universality and statistical validity of our results. Furthermore, one‐arm meta‐analysis is also regarded as a reliable method to provide level IIIa evidence 20,21,79,80 …”

“…Furthermore, one‐arm meta‐analysis is also regarded as a reliable method to provide level IIIa evidence. 20 , 21 , 79 , 80 …”

Brain Oedema Associated with Deep Brain Stimulation through a Single Directional Contact

“…It may be caused by mechanical trauma during surgery, accumulation of cerebrospinal fluid in the surgical tract or immunological hypersensitivity to implant materials. 3 To our knowledge, we are the first to report a case of noninfectious peri-electrode oedema, discovered 4 years postimplantation. This could potentially reflect either a detection delay (since interval imaging following the immediate postimplant MRI was not available) or a chronic inflammatory reaction to the materials used.…”

“…Peri-electrode oedema is now considered a common postoperative complication of DBS. 3,4 It typically develops within 3 months post-implantation and most patients remain asymptomatic. It may be caused by mechanical trauma during surgery, accumulation of cerebrospinal fluid in the surgical tract or immunological hypersensitivity to implant materials.…”