The occurrence of maedi-visna virus in Lebanon

Tabet, Elise; Tlaige, R; Abi-Rizk, Alain

doi:10.20506/rst.36.3.2723

Cited by 7 publications

(8 citation statements)

References 9 publications

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“…with SRLV infection in sheep that are absent of our study because no public publications from those countries were found, or they did not fulfilled the inclusion criteria. On the contrary, from 2005 to 2019, China, Costa Rica, Iran, Morocco, and Pakistan have never reported SRLV infection to the OIE and India, Lebanon, Czech Republic, Syria, and Turkey appear as “disease absent” despite available scientific descriptions from all these countries [ 20 , 21 , 23 , 24 , 25 , 26 , 27 , 29 , 30 , 33 , 34 , 35 , 55 , 67 ]. First reports on SRLV infection in Brazil according to OIE are from 2017, whereas scientific publications already reported the disease in 2007 [ 69 ].…”

Section: Discussionmentioning

confidence: 99%

“… 1 N, number of animals tested; 2 CI 95%, 95% confidence interval; 3 I 2 , heterogeneity statistic; 4 N/A, not applicable; 5 [ 25 , 26 , 28 , 29 , 31 , 33 , 35 ]; 6 [ 11 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 45 , 47 , 48 , 49 , 51 , 54 , 55 ]; 7 [ 57 , 58 , 59 , 61 , 62 , 63 , 64 , 65 , 66 ]; 8 [ 67 , 69 , 71 , 72 , 73 , 74 , 75 ]. …”

Section: Figurementioning

confidence: 99%

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Worldwide Prevalence of Small Ruminant Lentiviruses in Sheep: A Systematic Review and Meta-Analysis

Miguel

Arrieta

Rodríguez‐Largo

et al. 2021

Animals

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Small Ruminant Lentiviruses (SRLV) are highly prevalent retroviruses with significant genetic diversity and antigenic heterogeneity that cause a progressive wasting disease of sheep called Maedi-visna. This work provides a systematic review and meta-analysis of the last 40 years (1981–2020) of scientific publications on SRLV individual and flock prevalence. Fifty-eight publications and 314 studies were included. Most articles used a single diagnostic test to estimate prevalence (77.6%), whereas articles using three or more tests were scarce (6.9%). Serological tests are more frequently used than direct methods and ELISA has progressively replaced AGID over the last decades. SRLV infection in sheep is widespread across the world, with Europe showing the highest individual prevalence (40.9%) and being the geographical area in which most studies have been performed. Africa, Asia, and North America show values between 16.7% to 21.8% at the individual level. South and Central America show the lowest individual SRLV prevalence (1.7%). There was a strong positive correlation between individual and flock prevalence (ρ = 0.728; p ≤ 0.001). Despite the global importance of small ruminants, the coverage of knowledge on SRLV prevalence is patchy and inconsistent. There is a lack of a gold standard method and a defined sampling strategy among countries and continents.

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Section: Discussionmentioning

confidence: 99%

Section: Figurementioning

confidence: 99%

Worldwide Prevalence of Small Ruminant Lentiviruses in Sheep: A Systematic Review and Meta-Analysis

Miguel

Arrieta

Rodríguez‐Largo

et al. 2021

Animals

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“…VM is distributed in sheep industry across the globe and responsible for serious production loss. VM prevalence have been reported as 24.8% in Spain (Lago et al, 2012), 71% in Lebanon (Tabet et al, 2017), from 10.5 to 21.6% in Ethiopia (Ayalet et al, 2001), 28.8% in Germany (Huttner et al, 2017), from 20 to 60% in the UK (Ogden et al, 2019), 34.8% in Kosovo (Cana et al, 2020), and LIVESTOCK S T U D I E S from 3.3 to 96.7% in Canada (Heinrichs et al, 2017). In Turkey prevalence of VM was reported between 2.7 to 77.9% (Burgu and Toker, 1990;Yavru et al, 2012;Muz et al, 2013).…”

Section: Introductionmentioning

confidence: 98%

Evaluation of Two SNP Markers in DPPA2 and SYTL3 Genes for Association with Host Response against Visna/Maedi Infection in Turkish Sheep

Yaman¹

2020

Lalahan Hayvancılık Araştırma Enstitüsü Dergisi

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Visna/maedi (VM) is an incurable viral disease of sheep causing serious production losses across the globe. Classical control measures against VM such as screening and culling are costly and time-consuming. Breeding VM resistant sheep could provide an opportunity for struggling with the VM and decreasing the economic loss. In this study, we aimed to investigate possible associations between two previously reported single nucleotide polymorphisms (SNPs) in the ovine DPPA2 and SYTL3 genes and VM serostatus, and evaluate implementation of selective breeding strategies against VM in Karacabey merino, Kivircik, Imroz, and composite breeds; Bandirma, Hampshire crosses (HAMP), Ramlic and Black-headed German mutton crosses (SBA) which are reared in Marmara region of Turkey. For this purpose, we genotyped the sheep which VM serostatus were determined previously. The genotyping results showed that these SNPs in the DPPA2 and SYTL3 genes are polymorphic. We have conducted an association analysis with an experimental design using case-control matched pairs. Finally, a power analysis was performed to determine the power of the statistical analysis. According to our findings, within our detection limits (the minimum odds ratio 2.5 to 2.8; CI 95; statistical power 0.96; p-value < 0.05), there was no significant association between the SNPs in the DPPA2 and SYTL3 genes and VM serostatus. Therefore, these SNP markers are not useful to selective breeding against VM in Turkish sheep.

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“…Visna/maedi (VM) has been reported in Europe 4 , 5 , North America 6 , South America 7 , Asia 8 , and Africa 9 , 10 . Only New Zealand and Australia are yet VM free, nonetheless, these countries are suffering from CAEV 11 .…”

Section: Introductionmentioning

confidence: 99%

A novel 2 bp deletion variant in Ovine-DRB1 gene is associated with increased Visna/maedi susceptibility in Turkish sheep

Yaman¹,

Bay²,

Aymaz³

et al. 2021

Sci Rep

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Visna/maedi (VM) is a multisystemic lentivirus infection of sheep that affecting sheep industry across the globe. TMEM154 gene has been identified to be a major VM-associated host gene, nevertheless, a recent study showed that the frequency of the VM-resistant TMEM154 haplotypes was very low or absent in indigenous sheep. Thus, the present study was designed to determine other possible co-receptors associated with VM. For this purpose, DRB1 gene, which is renowned for its role in host immune response against various diseases was targeted. A total number of 151 case–control matched pairs were constructed from 2266 serologically tested sheep. A broad range of DRB1 haplotype diversity was detected by sequence-based genotyping. Moreover, a novel 2 bp deletion (del) in the DRB1 intron 1 was identified. For the final statistic, the sheep carrying VM-resistant TMEM154 diplotypes were removed and a McNemar’s test with a matched pairs experimental design was conducted. Consequently, it was identified for the first time that the 2 bp del variant is a genetic risk factor for VM (p value 0.002; chi-square 8.31; odds ratio 2.9; statistical power 0.90) in the dominant model. Thus, negative selection for 2 bp del variant could decrease VM infection risk in Turkish sheep.

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The occurrence of maedi-visna virus in Lebanon

Cited by 7 publications

References 9 publications

Worldwide Prevalence of Small Ruminant Lentiviruses in Sheep: A Systematic Review and Meta-Analysis

Worldwide Prevalence of Small Ruminant Lentiviruses in Sheep: A Systematic Review and Meta-Analysis

Evaluation of Two SNP Markers in DPPA2 and SYTL3 Genes for Association with Host Response against Visna/Maedi Infection in Turkish Sheep

A novel 2 bp deletion variant in Ovine-DRB1 gene is associated with increased Visna/maedi susceptibility in Turkish sheep

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