The ocular surface drug correction in patients after LASIK

Abstract

Purpose Optimization the ocular surface after LASIK Methods Assessed the ocular surface, tear film and tear production before and after optimization in patients after two‐step LASIK in 4 groups. Group 1 (A) ‐ high myopia and low degree of astigmatism ‐ (43), aged 18 to 35 years, group 2 (B) ‐ medium myopia and low degree of astigmatism – (32), aged 18 to 35 years, group 3 (C) ‐ myopia medium or high and medium degree of astigmatism – (37), older than 35 years, group 4 (D) ‐ hypermetropia medium or high and medium degree of astigmatism ‐ (32), older than 35 years. The criteria for preoperative drug correction of refractive surgery to the stage were the following diagnostic blocks: clinical data in diagnosis of dry eye and corneal status, corneal thickness, the definition of clinical refraction, including patient age, antioxidant and immune activity of tears. Results The use of moxifloxacin 0.5% and tear lubricants (such as preparation containing hydroxypropylguar and sorbitol or hydroxypropylguar) in groups A and В, and the use of tear lubricants (such as preparation containing hydroxypropylguar and sorbitol or hydroxypropylguar) in groups C and D after LASIK reduces residual astigmatism and the number of complications refractive surgery. Conclusion We found the dependence tear lubricants choice for optimizing the ocular surface after LASIK from the indices of corneal status, corneal thickness, the definition of clinical refraction, degree of astigmatism, including patient age, antioxidant and immune activity of tears. Pathogenetically substantiated using of preparations containing hydroxypropylguar and sorbitol or hydroxypropylguar after LASIK reduces the degree of residual aberrations.