The olive (Olea europaea L.) industry in China: its status, opportunities and challenges

Seasonal Variations in the Chemical Composition of Liangshan Olive Leaves and Their Antioxidant and Anticancer Activities

“…Olive trees (Olea europaea L.), belonging to the family Oleaceae, are one of the important economic crops all over the world [1]. In 1960, olive trees were introduced from the Mediterranean region into China as a commercial crop [2,3]. According to statistical analysis, almost 80,000 hectares of olive trees were cultivated by the end of 2017, generating approximately 600,000 tons/year of abandoned leaves in China [4,5].…”

Nanomaterials for molecular signal amplification in electrochemical nucleic acid biosensing: recent advances and future prospects for point-of-care diagnostics

“…108 They observed a 1000-fold enhancement in the detection limit (3.8 aM) of short DNA sequences in buffer when loading the organometallic compounds on gold nanoparticles. 108,109 A variety of nanoparticle-marker systems have been reported in recent years, including gold nanoparticles with methylene blue 110 or ferrocene, 111 Fe 3 O 4 nanoparticles with thionine or ferrocene, 112 multi-walled carbon nanotubes with thionine, 113 polymer nanoparticles with Cu 2+ ions, 114 and titanium phosphate nanoparticles with Cd 2+ ions. 49 More recently, versatile nanoporous MOFs have demonstrated high loading capacities for a variety of redox reporters, including ions (e.g.…”

“…methylene blue, 3,3′,5,5′-tetramethylbenzidine). 116,117 Interactions between redox markers and nanoparticles include covalent bonds, 112,113 electrostatic interactions, 49 nanopore intercalation, 114,115 physisorption, 116,117 and goldthiol interactions, 110,111 which control the loading process. The ability to load nanoparticle labels with several signal probes, such as Cd 2+ /Pb 2+ or methylene blue/ferrocene, enables a ratiometric signal analysis, using a dual-probe system to detect the ratio of the probe signal with respect to a reference.…”

“…By using a ferrocene labelled hairpin probe on an electrode surface, and methylene blue on the nanoparticle tag, detection of the target analyte is more robust, since nonspecific adsorptions events of the nanoparticle labels on the electrode can be accounted for from the signal ratio. 110 More generally, recent research efforts have been focused on surface engineering of nanoparticle labels, with a view to increasing the loading capacity of redox indicators. For example, one can functionalize gold nanoparticles with dsDNA or ssDNA to increase the number of possible binding sites for RuHex 118 or methylene blue labels, 119 respectively.…”

A Novel Electrochemical Aptasensor for Carcinoembryonic Antigen Detection Based on Target‐induced Bridge Assembly

“…Among different aptamer‐based techniques, electrochemical aptasensors have been commonly used for routine analysis because of their simple signal production, high sensitivity and easy fabrication .…”