The opiate addiction test: a clinical evaluation of a quick test for physical dependence on opiate drugs.

Ghodse, Hamid; Taylor, Denise; Greaves, Jane; Britten, A. J.; Lynch, David

doi:10.1111/j.1365-2125.1995.tb04445.x

Cited by 13 publications

(6 citation statements)

References 6 publications

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“…It is well known that some ophthalmic drugs are easily absorbed into the systemic circulation. There is a report of the efficacy of ocular administration of naloxone in humans associated with heroin abuse (Duncalf et al 1975, Ghodse et al 1995. In animal experiments, sufentanil (Farnsworth et al 1998, Malek et al 2011, buprenorphine (Malek et al 2012), and fentanyl (Zöllner et al 2008) have been tested, and remifentanil was tested in our pilot study (Malek et al 2012).…”

Section: Non-traditional Routes Of Administration Of Remifentanil Andmentioning

confidence: 99%

Non-Traditional Administration of Remifentanil in an Experimental Setting

Kurzova

Málek²,

Hess³

et al. 2019

Physiol Res

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Remifentanil is ultrashort-acting opioid with a unique pharmacokinetic profile. It is used exclusively intravenously. While considering its rapid onset of action and other pharmacokinetic properties, we decided to assess its effects following administration via non-traditional routes. Rabbits (n=10 per each group) were randomized into six groups: remifentanil 1 μg/kg and 3 μg/kg IM, 5.0 and 10.0 μg/kg conjunctivally, and 10 μg/kg and 25.0 μg/kg intranasally. Sedating effects were assessed via a loss of the righting reflex. Secondary, mean arterial blood pressure, arterial oxygen saturation of hemoglobin, and pulse rate was monitored in all rabbits. Non-traditional routes of administration were shown to provide a rapid onset of action as well as fast recovery. Importantly, the administration of remifentanil did not result in any deterioration of cardiovascular functions.

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Section: Non-traditional Routes Of Administration Of Remifentanil Andmentioning

confidence: 99%

Non-Traditional Administration of Remifentanil in an Experimental Setting

Kurzova

Málek²,

Hess³

et al. 2019

Physiol Res

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show abstract

“…It was exhibited at the Millennium Dome in 2000, it won the Trade and Industry SMART and SPUR Awards, and was also the runner-up for the Aneurin Bevan NHS Award. The pupillometer part of the opiate addiction test is now being manufactured by Procyon [20][21][22][23].…”

Section: A: So How Did You Approach This Problem? Hgmentioning

confidence: 99%

Conversation with Hamid Ghodse

2007

Addiction

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“…He developed a quick, non-invasive and reliable test to determine levels of opiate addiction by measuring pupil size [3][4][5]. In medical education, he led the establishment of a range of undergraduate, postgraduate and multiprofessional training programmes in addiction.…”

mentioning

confidence: 99%

A. Hamid Ghodse (1938–2012)

Schifano

2013

Addiction

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The opiate addiction test: a clinical evaluation of a quick test for physical dependence on opiate drugs.

Cited by 13 publications

References 6 publications

Non-Traditional Administration of Remifentanil in an Experimental Setting

Non-Traditional Administration of Remifentanil in an Experimental Setting

Conversation with Hamid Ghodse

A. Hamid Ghodse (1938–2012)

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