Since a great number of star stream and substructures near M31/M33 have been discovered in Pan-Andromeda Archaeological Survey (PAndAS) and variations of star stream density may trace the dark matter sub-halos, it is good opportunity to study the dark matter sub-halos with the star streams. Further it has been proved that dozens of halo star clusters have the relations with the star stream. As Prime Focus Spectroscopy (PFS) of the 8.2-m Subaru telescope have the powerful ability (I ∼ 22.3 mag) to observe ∼ 2400 objects at a time, it can be used to observe the giant star streams, faint halo star clusters and dwarf galaxies, which provides excellent opportunity to investigate the sub-halos of M31. In addition, we are involved with the Local Volume Mapper (LVM) of SDSS-V program, which may also provide more informations for the star clusters of the Local Group, especially for M31. Finally since we have done series of work with Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST), we will continue the spectroscopic observations for more star clusters and giant stars of M31/M33.