The PedsQL™ in Type 1 and Type 2 Diabetes

Varni, James W.; Burwinkle, Tasha M.; Jacobs, Jenifer R.; Gottschalk, Michael; Kaufman, Francine; Jones, Kenneth L.

doi:10.2337/diacare.26.3.631

Cited by 520 publications

(479 citation statements)

References 15 publications

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“…Baseline total HRQOL in our study participants was comparable to that of previous studies using the PedsQL in youth with type 2 diabetes [33,46]. Despite the strict and difficult nature of a VLED, quality of life improved from baseline to 8 weeks.…”

Section: Quality Of Life and Eating Behaviourssupporting

confidence: 73%

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Reversal of type 2 diabetes in youth who adhere to a very-low-energy diet: a pilot study

et al. 2016

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Aims/hypothesis The aim of the study was to investigate whether a very-low-energy diet (VLED) is a feasible and acceptable treatment option for type 2 diabetes in children and adolescents, and whether adherence can lead to rapid weight loss, reversal of type 2 diabetes and reduced liver fat as seen in adult studies. Methods Eight participants with type 2 diabetes and obesity, aged 7-16 years, non-medicated (n = 1) or treated with metformin (n = 7) and in some cases insulin (n = 3), followed a VLED (<3360 kJ/day) for 8 weeks, then transitioned to a hypocaloric diet (∼6300 kJ/day) that they followed to 34 weeks. HbA 1c , fasting glucose and 2 h post-glucose load plasma glucose (2hG) were determined from fasting blood and an OGTT. Liver fat concentration was quantified using proton magnetic resonance spectroscopy. Adherence was defined as ≥5% weight loss during the 8 week VLED. Results Adherers (n = 5) and non-adherers (n = 3) had median weight loss of 7.5% and 0.5%, respectively, at 8 weeks. Only three out of eight participants met non-alcoholic fatty liver disease (NAFLD) criteria (≥5.5%) at 8 weeks, compared with eight out of eight at baseline. The three participants on insulin therapy at baseline were able to cease therapy during the 8 week VLED. At 34 weeks, adherers (n = 5) achieved 12.3% weight loss, none met NAFLD criteria and four did not meet American Diabetes Association criteria for type 2 diabetes.

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Section: Quality Of Life and Eating Behaviourssupporting

confidence: 73%

“…Quality of life and eating behaviours Health-related quality of life (HRQOL) and psychological dimensions of eating behaviours were self-reported using the validated Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales [33] and Dutch Eating Behaviour Questionnaire for Children, respectively [34].…”

Section: Assessmentsmentioning

confidence: 99%

Reversal of type 2 diabetes in youth who adhere to a very-low-energy diet: a pilot study

et al. 2016

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“…The PedsQL is a valid measure of physical function and psychosocial health in many groups of children aged 2 to 18 years [55][56][57][58][59][60][61], including those with chronic disease [9,34,43,55,58,59,61]. In children with musculoskeletal conditions, the PedsQL is responsive and accurately shows change over time [12,[56][57][58][59].…”

Section: Methodsmentioning

confidence: 99%

Lower Extremity Pain Is Associated With Reduced Function and Psychosocial Health in Obese Children

Bout-Tabaku

Briggs

Schmitt

2013

Clinical Orthopaedics &Amp; Related Research

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Background Childhood obesity is associated with reduced quality of life, physical fitness, and a higher prevalence of lower extremity (LE) pain; however, it is unclear whether and how these factors are related. Questions/purposes For this study we asked if obese children with LE pain (LE+) had higher BMI-Z scores, lower physical function and psychosocial health, and lower physical fitness compared with obese children without LE pain (LEÀ). We determined the association of BMI-Z score with physical function, psychosocial health, or physical fitness in obese children.

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“…The DM has five subscales: diabetes symptoms (eleven items), treatment barriers (four items), treatment adherence (seven items), worry (three items), and communication (three items (17).…”

Section: Measurementsmentioning

confidence: 99%

Benefits of Continuous Subcutaneous Insulin Infusion on Quality of Life

Lukács

Kiss-Tóth

Varga

et al. 2012

Int J Technol Assess Health Care

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Purpose: The aim of this study was to compare the general health-related quality of life (HRQoL), the metabolic control (HbA 1c ), the anthropometric measurement, and the cardiorespiratory fitness (expressed by VO 2max ) in youths with type 1 diabetes treated with continuous subcutaneous insulin infusion (CSII) to those receiving multiple daily injections (MDI). We looked for factors influencing the HRQoL and metabolic control. Methods: A total of 239 patients treated with CSII (51 girls and 53 boys) or MDI (64 girls and 71 boys) between ages 8 and 18 years were assessed with the Pediatric Quality of Life Inventory, Generic Core Scales, and Diabetes Module. VO2max was evaluated using the 20-meter shuttle run test. Results: CSII group had significantly better HRQoL according to both child self-report and parent proxy-report. Youths with CSII reported better physical, emotional, and school-related functioning, and had less diabetes-related fear and symptoms than the MDI group. There were no significant differences in body mass index z-scores, insulin doses, HbA 1c , and VO 2max between the groups. HRQoL was predicted by the CSII therapy (β =−0.220; p < .001) and the VO 2max (β = 0.386; p < .001), other clinical and anthropometric parameters had no effect; the HbA1c was predicted only by VO2max (β =−0.353; p < .001). Conclusions: Diabetic youths treated with CSII therapy have better HRQoL than those treated with MDI. There are no differences between the investigated groups in anthropometric data, glycated hemoglobin, and physical fitness. Moreover, good physical fitness has an important role in achieving better metabolic control and HRQoL, which underlines the importance of regular aerobic exercise in the treatment and care of type 1 diabetes in childhood.

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The PedsQL™ in Type 1 and Type 2 Diabetes

Cited by 520 publications

References 15 publications

Reversal of type 2 diabetes in youth who adhere to a very-low-energy diet: a pilot study

Reversal of type 2 diabetes in youth who adhere to a very-low-energy diet: a pilot study

Lower Extremity Pain Is Associated With Reduced Function and Psychosocial Health in Obese Children

Benefits of Continuous Subcutaneous Insulin Infusion on Quality of Life

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