“…The first report of blood cell chimerism in twins 10 was published 50 years ago, and more than 100 cases have since been described in the literature 1,3 , 11 . However, most of the reported cases have dealt with serologic and/or genetic markers 12 . ‐15 In the present study, we describe a patient who developed an acute hemolytic transfusion reaction after the transfusion of a chimeric blood unit containing group O and only a small amount of group B RBCs.…”