The Potency of Antifertility Effect of Stem Bark Extract of Mangrove (Avicennia Marina) on Male White Rats (Rattus Novergicus)

Lolok, Nikeherpianti; Ikawati, Nurlena; Siharis, Fatmasari

doi:10.5220/0009587701410146

Cited by 2 publications

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“…In addition to its ecological role, A. marina is known to contain various secondary metabolic compounds like steroids, naphthalene, terpenoids, flavonoids, phenyl propanoid glycosides, diterpenoid glucosides, and glucoside iridoids [20,21]. These compounds exhibit antimicrobial, antioxidant, antiaging, antiinflammatory, antitumor, kidney anti-choline, antituberculosis, and anti-atherosclerotic properties [22]. Flavonoids, in particular, have anti-fertility properties.…”

Section: Introductionmentioning

confidence: 99%

“…Lolok et al [22] reported that A. marina stem bark extract was shown to have potential activity as an anti-fertility agent in male rats, as evidenced by a decrease in the number of spermatozoa, epididymal weight, viability, and motility. However, until now, there has been no report on the bioactive contained in A. marina, which acts as an anti-fertility agent, and in which tissues these compounds can be found.…”

Section: Introductionmentioning

confidence: 99%

“…22 bioactive compounds in the flowers and fruits of A. marina. The result aligns with the report[31] that A. Marina is rich in bioactive compounds, namely the aliphatic group alcohols and acids, hydrocarbons, amino acids, alkaloids, free fatty acids, carbohydrates, carotenoids, pheromone, phorbolesters, phenolics and related compounds, lipids, triterpenes, steroids, and their glycosides, tannins, and other terpenes.…”

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confidence: 99%

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Avicennia Marina: A Natural Resource for Male Anti-Fertility in Family Planning

Rodiani,

Duryat,

Maryono

et al. 2023

IJDNE

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Increasing male involvement in family planning is a strategic priority, with herbal antifertility agents offering a potential solution. Coastal communities have traditionally utilized the bark of Avicennia marina as an anti-fertility agent. This study aims to characterize the bioactive compounds present in A. marina tissues and assess their potential as male anti-fertility agents. This exploration of mangrove anti-fertility agents could address the issue of limited access to contraceptives among low-income individuals residing in coastal regions. A. marina samples were collected from the mangrove forests of Pasir Sakti Village, Lampung Timur Regency. The bioactive content was analyzed using Gas Chromatography (Agilent 6890 series GC -MS) equipped with an HP-5MS method. A total of 49 bioactive compounds were identified in A. marina using the GC-MS method and ethanol solvent for extraction. The highest diversity of bioactive compounds was observed in flowers and fruits, followed by wood, roots, leaves, and bark, containing 21, 14, 13, 13, and 8 compounds, respectively. A. marina demonstrated the potential to produce 36 types of flavonoids, compounds previously established as effective male anti-fertility agents. The majority of flavonoids were found in the root, followed by flowers and fruits, wood, leaves, and bark, with 14, 11, 11, 8, and 8 types, respectively. These findings suggest that A. marina possesses significant potential as a source of male anti-fertility agents, presenting an opportunity to increase men's participation in family planning, especially in low-income coastal communities.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Avicennia Marina: A Natural Resource for Male Anti-Fertility in Family Planning

Rodiani,

Duryat,

Maryono

et al. 2023

IJDNE

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“…The leaves of the plant have been potentially used as medical treatment for ulcers, abscess and burns [9]. It has been traditionally used to reduce arthritic pain [10] and used worldwide for the treatment of smallpox, snake-bites. Fruits of A. marina have been used for digestive disorders such as constipation.…”

Section: Introductionmentioning

confidence: 99%

Exploration of Antioxidant Effects of Crude Extract of Mangrove Plant - Avicennia marina

Lakshme

Roy

Sivaperumal

et al. 2021

JPRI

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Introduction: Antioxidants are efficient in the prevention of human diseases. Mangroves are high bioactive compounds with good holistic bioactivities including insecticides. Avicennia marina, a mangrove plant which has its origin in South Africa included in the family Acanthaceae. Aim: To explore the antioxidant potential of methanolic extract of mangrove plants, Avicennia marina. Materials and Methods: The fresh leaves of Avicennia marina were collected from Pichavaram mangrove forest area. The leaves were washed and then shade dried for 2-3weeks and turned into a fine powder. Crude methanolic extract of Avicenna marina was prepared. Total antioxidant activity, DPPH Assay and scavenging activity of hydrogen peroxide were performed and antioxidant potential was assessed using ascorbic acid as standard. Results: The scavenging activity increased with increase in concentration of the extract and thus antioxidant activity was dose dependent. The total antioxidant activity was more close to the ascorbic acid equivalence. Conclusion: This study concludes that the methanolic extract of Avicenna marina is capable of scavenging a wide range of free radicals for which it can be exploited for the treatment of various free radical mediated diseases. It is evident that mangrove species as a collective are rich sources of antioxidants, phenolics and antimicrobial compounds.

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The Potency of Antifertility Effect of Stem Bark Extract of Mangrove (Avicennia Marina) on Male White Rats (Rattus Novergicus)

Cited by 2 publications

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Avicennia Marina: A Natural Resource for Male Anti-Fertility in Family Planning

Avicennia Marina: A Natural Resource for Male Anti-Fertility in Family Planning

Exploration of Antioxidant Effects of Crude Extract of Mangrove Plant - Avicennia marina

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