Frequent floods and droughts, which cause significant material and intangible losses, are a result of watershed destruction especially in Central Sulawesi. Flash floods have been a common occurrence in portions of Central Sulawesi in recent years, and Miu Sub-watershed is one of those watersheds. Both the material and non-material effects were fairly significant, especially for the local population. The biophysical conditions of the area must be known in order to identify flood target areas and flood causes. The application of Geographic Information Systems is the technique used to assess floods. This study’s objective is a spatial examination of the Miu sub-watershed flood susceptibility. Flood-prone areas are analyzed using a variety of techniques, including overlaying, categorization, scoring, weighting, and modeling. The three types of flood danger classes are non-prone, medium, and prone. The Miu sub-watershed region has an area with a flood hazard class for the non-prone category of 64,255.173 ha, a medium category of 57,909.003 ha, and a vulnerable category of 4,838.917 ha. Bangga Village in Dolo Selatan Sub-district, Tuva Village in Gumbasa Sub-district, and Bolapapu Village in Kulawi Sub-district are the Miu Das regions with the widest category of high flood threat.