The potential role of formononetin in cancer treatment: An updated review

Aliya, Sheik; Alhammadi, Munirah; Park, Uichang; Tiwari, Jitendra N.; Lee, Jeong-Hwan; Han, Young-Kyu; Huh, Yun Suk

doi:10.1016/j.biopha.2023.115811

Biomedicine & Pharmacotherapy

2023

DOI: 10.1016/j.biopha.2023.115811

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The potential role of formononetin in cancer treatment: An updated review

Sheik Aliya,

Munirah Alhammadi,

Uichang Park

et al.

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Cited by 11 publications

References 80 publications

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Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies

Selepe

2024

ChemMedChem

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Isoflavones are phenolic natural compounds with a C6C3C6 framework. They possess a plethora of biological activities that are associated with putative benefits to human health. In particular, the cancer chemopreventive and chemotherapeutic potential of isoflavones has attracted the interest of researchers. Several isoflavone derivatives have been synthesised and probed for their anticancer activities. The isoflavone analogues are mainly synthesised by molecular hybridisation and other strategies that enable diversification through early or late‐stage functionalisation of A‐, B‐ and C‐rings of the isoflavones. This has resulted in the discovery of isoflavone analogues with improved antiproliferative activities against several cancer cells and different mechanisms of action. In this review, the synthesis of isoflavone derivatives and their anticancer activity studies are discussed.

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Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies

Selepe

2024

ChemMedChem

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Identification of Dalbergiae Odoriferae Lignum active ingredients and potential mechanisms in the treatment of adriamycin-induced cardiotoxicity based on network pharmacology and experimental verification

Luan,

Ding,

Zhang

et al. 2024

Naunyn-Schmiedeberg's Arch Pharmacol

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An overview on the potential application of nanotechnology in enhancing the therapeutic efficacy of phytoestrogens

Joshi,

Kathuria,

Paul

et al. 2025

Food Chemistry

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The potential role of formononetin in cancer treatment: An updated review

Cited by 11 publications

References 80 publications

Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies

Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies

Identification of Dalbergiae Odoriferae Lignum active ingredients and potential mechanisms in the treatment of adriamycin-induced cardiotoxicity based on network pharmacology and experimental verification

An overview on the potential application of nanotechnology in enhancing the therapeutic efficacy of phytoestrogens

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