2011
DOI: 10.1016/j.ejca.2011.02.022
|View full text |Cite
|
Sign up to set email alerts
|

The preclinical and clinical activity of aviscumine: A potential anticancer drug

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
31
0

Year Published

2013
2013
2023
2023

Publication Types

Select...
8
2

Relationship

2
8

Authors

Journals

citations
Cited by 44 publications
(31 citation statements)
references
References 36 publications
0
31
0
Order By: Relevance
“…The high IFN-γ response indicates that rML administration stimulates Th1 cells, which may mediate an antitumor T-cell response (reviewed by Zwierzina et al . [19]).…”
Section: Overview Of Immunomodulatory Plant Lectinsmentioning
confidence: 99%
“…The high IFN-γ response indicates that rML administration stimulates Th1 cells, which may mediate an antitumor T-cell response (reviewed by Zwierzina et al . [19]).…”
Section: Overview Of Immunomodulatory Plant Lectinsmentioning
confidence: 99%
“…Regarding to the biological role of lectins, it appears that they are made to act in the inside and in the outside of the plants, as a tool or reaction mediators including agricultural (plant defense against the pathogens) (Peumans & Van Damme, 1995), immunology (antimicrobial and immunomodulatory) ( Ryder et al, 1992;Wang et al, 1996;Rubinstein et al, 2004;, serology (identification blood cell banks) (Boyd & Shapleigh, 1954;Khan et al, 2007;Meite et al, 2008), cancer (histochemical markers such as cancer and toxicity of cancer cell lines) (Guillot et al, 2004;Liu et al, 2010;Zwierzina et al, 2011), biochemistry (characterization, isolation and purification) (Hirabayashi, 2004;Peumans & Van Damme, 1998), and other biological field (reserve role, hormonal mimicry and enzymatique mimicry) (Meite et al, 2006).…”
Section: Introductionmentioning
confidence: 99%
“…Both microorganisms are well-established platforms for the production of recombinant proteins, including several approved biopharmaceutical products (Berlec and Strukelj, 2013; Gasser et al, 2013). These are also the most employed hosts for the production of recombinant lectins, namely plant lectins for biomedical purposes, such as jacalin (Sahasrabuddhe et al, 2004, 2006), aviscumin (from Viscum album ; Zwierzina et al, 2011), PCL (from Polygonatum cyrtonema ; Li et al, 2011), Orysata (from Oryza sativa ; Al Atalah et al, 2011), and GNA maize (from Galanthus nivalis ; Fouquaert et al, 2009). E. coli is commonly used to produce non-glycosylated lectins, while P. pastoris is mainly employed to overcome problems of insoluble expression of the bacterial system and to produce glycosylated lectins.…”
Section: Outlinementioning
confidence: 99%